Sir one of my esrd patient showing positive result for anti-hcv test for last 3 months. A test hcv-rna quantitive was performed 3 months back when he was first diagnosed anti hcv positive but hcv-rna is negative. What are the further suggestions for the patient? should I start doing hemodialysis on positive machines or should I wait till hcv-rna is positive. How frequently I must repeat hcv-rna as it is very costly for the patient and not willing for such test. Hcv-rna quantitive or qualititive, which should be more confirmatory test for him. When the patient must start taking treatment for hepatitis-c.