My wife is a sugar patient since dev. 2007 in first time doctor prescribe citapin xr500 after lunch one time. In 2009 doctor chang his dose one after lunch and one after dinner that time sugar level is 110 fasting and 140 pp. After 2011 onec again dose was changed citapin xr500 and glimer 1mg with lunch and citapin xr 500 at dinner this time sugar level is 110/140 and doctor start caditor (atervovastitin) 5mg ciplar la 20mg and telmikind h. In 2014 november my wife stop taking glimer 1mg tablet in january 2015 sugar level is 220/279 this was very high so we go to our doctor doctor changed sugar medicine this was gluformin g2 but sugar level was not drop this was 239/190. And h1bc level is 2.3. In febuary 2015 sugar level 290/331 and c peptide level is 1.2 from march 2015 she is taking galvas 50 and dimecron xr 500 max with lunch and dinner with regular medicine ciplar la20 and caditor 5mg telmikind h at night. Dear respected doctor my question is this are this medicine are safe for long time use for sugar treatment