My mother had adenocarcinoma of lung which was diagnosed on 5/6 when pet ct was performed and has egfr mutation in exon 19. She also has neurological symptoms like vision loss, hearing loss, vomiting and headache. There is suspicion of metastatic to brain but csf cytology has been negative for 5 consecutive times at regular intervals. How can we confirm if it has metastized or no?

Dr. Nikhilesh BorkarOncologist14yrs exp

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MRI brain was done? Usually it is diagnosed on mri rather than CSF cytology. Pet ct is not good to detect brain mets. What is the pet report? What is the local stage and any mets? If metastatic or advanced inoperable, since the egfr mutation is present, she is a candidate for Geftinib or preferably osimertinib. I would be able to opine better if you could share all her reports. Feel free to contact me directly if you want to discuss this further.  

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