Hi, My husband aged 51. Diagnosed case of carcinoma Colon completed 12 cycles of chemotherapy (July 2017) with FOLFOX 6 Q2 post surgery (December 2016). Relapsed again in November PetCT (29november 2017) showed soft tissue deposits in perihepatic, perisplenic, omental, mesentery, pelvis and ascites are new findings. FNAC: s/o moderately diff adenocarcinoma. Doc planned 6 cycles of chemo with Folfiri n added Avastin targeted therapy during 2nd round of chemo completed today. Please advise me the effective course of treatment to be given The patient. Whether Immunotherapy will be helpful in this case?