Dear Sir/Madam, I had suffered from hepatitis ?E? along with leptospirosis infection in the year 2011. Post recovery I was feeling very weak along-with very much weakness in the body. As the passing of the time I usually felt good and my weight has also been increased. Doctor told to make to take everything in the diet. But from the last 3-4 years I am experiencing lots of changes in my body like poor digestion, excessive gas, bloating, indigestion, loose stool with mucus, 5-6 times visiting the toilet, fatigue,lethargy, weakness in the body, irritability,fear, nervousness,easily stressed out. Not able to get sound sleep at nights. I got a very weak immune system also. Visited lots of doctors here in Mumbai. Some doctors says I got physiological problems. Some says I have gastritis, some says I have IBS, some says that I must be having amoebiasis or H.Pylori infections. Some says that there is inflammation in the intestines and my intestines are weak. I am not getting proper solution to my problem. At times I am feeling very much depressed. I do not know what to do. I am feeling hopeless. I do not know what had happened to my body. Nobody able to properly diagnose the problem which I am having. I do not have any bad habits. I do not smoke, drink etc. But still I am so much problem in my body. Further, below are the test performed in order to rule out. OGD SCOPY + is can + biopsy PERFORMED OGD Scopy was considered to evaluate exact etiology of patients symptoms of Upper G.I.Tract. OGD Scopy revealed mild lax cardia with frank reflux. Stomach showed erosive gastritis with atrophic antral mucosa. Erosions were seen in the fundus and antrum. Chronic duodenitis was seen in the duodenal bulb and proximal duodenum. Biopsy was taken from antrum for H.Pylori. Comments: Endoscopic findings are suggestive of mild GERD with erosive gastritis with atrophic antral mucosa and chronic duodenitis. Patient will require dietary and lifestyle modifications apart from supportive medication for the same. Patient will require clinical follow up after 1 month. Biopsy confirmed for H.Pylori. ILEO-COLONOSCOPY+ is can+POLYPECTOMY PERFORMED Ileo-Colonoscopy was considered to evaluate exact etiology for patients complaints of 3-4 semi solids with blood streak stools. Adequate bowel preparation was done. Scope was passed up to terminal ileum, which essentially appeared normal. Multiple biopsies were taken from colon and sent for HPE. Left sided colon appeared spastic. Erosive proctitis was seen in rectum. 2 polyps were noted on the stapled line on previously done hemorrhoidectomy which was sent for histopathology. Comments: Ileo-colonoscopy findings are suggestive of irritable spastic left bowel with erosive proctitis and 2 polyps at the stapled line which can explain patients symptoms of blood streak stools. Biopsy material may provide additional information for further management. Patient will require reassurance apart from supportive medical care. Patient will require clinical follow up after 1 month. HISTOLOGY REPORT Specimen:1.Biopsies from the colon 2. Polyp from the rectum Gross:1. Three tiny bits aggregate to 0.4 cm. 2. Few polypoid grayish bits aggregate to 0.4 cm. Microscopic: 1. The colonic mucosa reveals orderly tubules. The lamina propria contains a mononuclear inflammatory infiltrate admixed with eosinophil and a focal lymphoid aggregate. 2. The polypoid bits are focally covered by a colonic mucosa. The lamina propria shows congested blood vessels and a moderate mononuclear inflammatory infiltrate admixed with neutrophil few eosinophil. No adenomatous change is seen. There is no evidence of dysplasia or malignancy. Diagnosis.1. COLON ? MILD colitis 2. RECTUM ? INFLAMMATORY POLYP.