Suffering form depression from long time, tried different antidepressants nexito, vilano currently on bupropion. Bupropion has lifted few of the symptoms but not completely. M from medical profession and read about melancholic depression and I am having most of the symptoms related to it like anhedonia, early morning awakening, depression more severe in the morning. I wanted to know, what's the success rate of melancholic depression with bupropion or other AD. Tca has got better result compared to other drugs. What about fluoxetine? Or venflaxine So shall I give a try to TCA .and any other tips in particular to melancholic depression.

Depression

1Doctor Answered

Dr. Saranya DevanathanPsychiatrist46yrs exp

92% (1295 ratings)

Ask Free Question

Dear lybrate-user, Most antidepressants work more or less at the same level. Mostly, you go by the side-effects - whether they are acceptable by you. Both Vilazodone and Bupropion have minimal sexual side effect. Fluoxetine has more erectile dysfunction. Weight and sedation are also to be taken into account. If you can tolerate effective dose of TCA, you can try. Otherwise go for Venlafaxine. The only tip is - it is not the antidepressant. It is the duration (minimum 3-6 weeks) and dose (TCA and Venlafaxine 75 - 225 mg) of the tablet that matters.

0 person found this helpful

Was this answer helpful?

YESSOMEWHATNO

Health issues vary person to person

Take help from the best doctors

Find Doctors near youBook appointment with top doctors

Ask a FREE QuestionGet Answers from doctors with 24 hours

Get Health Products @LOWEST PRICESGet 80% CASHBACK

Suggestions offered by doctors on Lybrate are of advisory nature i.e., for educational and informational purposes only. Content posted on, created for, or compiled by Lybrate is not intended or designed to replace your doctor's independent judgment about any symptom, condition, or the appropriateness or risks of a procedure or treatment for a given person.