I am pregnant My LMP is 27/12/2016. On 18th April (16 week) I have fever with rashes. On 22th april blood test Rubella IgM titre is 46.1 positive, on 28th April Rubella IgM titre is 132 positive, on 12th May Rubella IgM titre is 129 positive, on 18th May Rubella IgM titre is 125 positive. IgG is negative. IgG avidity is 3%. I have tension about baby infection and abnormalities. The anomaly scan on 9th May is normal pls suggest about baby. Kya abnormalities ke chances hai.
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The presence of IgG antibody against rubella is a sign that the patient has had the disease at some point in life and now is immunized. The presence of IgG antibodies is often called a serological scar, or a mark that the patient was infected in the past. The existence in the blood of large amounts of IgM antibodies against rubella, for example, is an indication that infection has recently been acquired. So a serology IgM positive result for rubella indicates ongoing infection. When the patient makes a serology rubella, there are basically three possible outcomes: 1. IgM and IgG non-reactive.
2. IgM reactive and IgG non-reactive.
3. IgM non-reactive and IgG reactive.
1. What does the result: IgM and IgG non-reactive? If in your serology rubella both IgM and the IgG come as no reagents, it means you do not have antibodies against rubella, or has never been exposed (a) to this virus and is susceptible to an infection. If you have been vaccinated (a), but its IgG is non-reactive, it means that vaccination was not effective, which is an indication to repeat the vaccine. A pregnant woman who has negative serology for rubella need to be very careful not to come into contact with anyone infected, because, as she has no antibodies against rubella, it runs the risk of contamination during pregnancy. Therefore, a pregnant with positive serology for IgM means she probably infected with the rubella virus in the last 2-6 weeks, being at risk of having a fetus with malformations, especially if the pregnancy is in the first quarter. In your case it is clear that IgM is increasing initially meaning a recent infection and hence affecting the fetus Reference values for rubella IgM: No reactive: less than 0.6 IU / mL
Undetermined: 0.6 to 0.79 IU / mL
Reactive: greater than 0.79 IU / mL
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