I am having very severe knee pain problems on my right knee from the past many months, due to which I cannot walk much & also unable to stand for a longer period/duration due to such knee pain. The X-ray reports of my both the knee (as on dated 26.10.2016) says the under-mentioned three things: 1. Digitogram reveals mild OA changes noted involving both knee joints. 2. The patella-femoral compartments show early affection. 3. Joint spaces of the knees are normal. I had tried lots & lots of medicines from the past two years in order to reduce my severe knee (joint) pain problems, but all the medicines had totally/completely failed & none of them had really worked or had helped me or either reduced my severe knee pain problems. I had also gone to many best orthopaedics doctors (nearly six to seven) of Kolkata during these past two years but the medicines prescribed by all of them (i.e these orthopaedics doctors) had not really helped me, even in the least manner or to the least level. I have heard from lots of people that, the medicine named" Macvestin"is very good & extremely helpful in reducing severe & continuous knee (especially joint) knee pain problems. Should I start taking this" Macvestin"tablet/medicine. If yes, then which" Macvestin"tablet should I start with i.e either 500 mg or 1000 mg. Please advice. How many tablets should I consume within 24 hours i.e one tablet or two tablet - i.e within a day. Is this tablet is to be taken/consumed - after eating breakfast, lunch or dinner. Please advice/suggest my all these above-mentioned queries in detail - in my email id .i.krishnakumar.chaturvedi@gmail.com krishnakumar. Chaturvedi@gmail.com"My mobile no. Is" 9674458740"& your goodself can make a call to my mobile no. On any day & at any time. KRISHNA KUMAR CHATURVEDI.