Hello doc, I am 21 years old and I have leukoderma problem since 10 years I have tried all type of medications allopathic, homeopathic, ayurvedic, laser treatment. Bt all these proved useless now its getting worse for me to handle this problem please suggest something so that I can get rid of it soon.

Dr. Sandesh GuptaDermatologist22yrs exp

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Hii lybrate-user .there is no need to get disheartened. Leukoderma is treatable and majourity of patients have gained good results through proper treatment. Four options are currently available for the treatment of vitiligo: sunscreens; cover-up; restoration of normal skin color; and bleaching of normal skin with topical creams to remove normal skin pigment to make an even color. Sunscreens The two goals of sunscreen treatments are: to protect unpigmented involved skin from sunburn reaction and to limit the tanning of normal pigmented skin. The sun protection factor (SPF) of sunscreens should be no less than SPF 30, as this grade blocks not only erythema, but also the affects of sunlight on the DNA of the skin cells. Cover-up The goal of cover-up with dyes or make-up is to hide the white macules so that the vitiligo is less visible. Self-tanning lotions and camouflage are quite helpful for some patients. Restoring Normal Skin Color Restoration of normal skin color can take the form of spot treatments or whole body treatment. Spot Treatment: Topical Corticosteroid Creams Initial treatment with certain topical corticosteroid creams is practical, simple, and safe. If there is no response in 2 months, it is unlikely to be effective. Physician monitoring every 2 months for signs of early steroid atrophy (thinning of the skin) is required. Spot Treatment: Skin Grafting Skin grafting involves transplanting the patient's normal skin to vitiligo affected areas, may be a useful technique for refractory segmental vitiligo macules. PUVA may be required following the procedure to unify the color between the graft sites. Whole Body Treatment: PUVA Photochemotherapy (Oral Psoralens + UVA Irradiation) For more widespread vitiligo, treatment with oral psoralen + UVA (PUVA) is practical. This may be done with sunlight and trimethylpsoralen (Trisoralen) or with artificial UVA (in the doctor's office or at an approved phototherapy facility) and Trisoralen or Oxsoralen-Ultra. PUVA is up to 85% effective in over 70% of patients with vitiligo of the head, neck, upper arms, legs, and trunk. Maintenance treatments are required.  

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