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THROMBOTIC THROMBOCYTOPENIC PURPURA
Thrombotic thrombocytopenic purpura (TTP or Moschcowitz syndrome is a rare disorder of the blood-coagulation system, causing extensive microscopic clots to form in the small blood vessels throughout the body.These small blood clots, called thrombi, can damage many organs including the kidneys, heart and brain. Symptoms may include any of the following:
• Bleeding into the skin or mucus membranes
• Fatigue, weakness
• Pale skin color or yellowish skin color
• Shortness of breath
• Fast heart rate (over 100 beats per minute)
HOW IS THROMBOTIC THROMBOCYTOPENIC PURPURA DIAGNOSED?
Diagnosing TTP usually requires multiple tests including a physical exam. Blood tests to check for conditions of the red blood cells and platelet count and levels of bilirubin. Blood is checked for antibodies, which are proteins that interfere with the enzyme ADAMTS13, creatinine levels and lactate dehydrogenase
HOW IS THROMBOTIC THROMBOCYTOPENIC PURPURA TREATED?
The treatment of Thrombotic Thrombocytopenic Purpura typically involves attempting to return the blood clotting ability to normal. The usual treatment is to administer plasma intravenously or through an IV. Besides medication, Thrombotic Thrombocytopenic Purpura is also treated through plasma exchange.
DID YOU KNOW?
Complications may include:
• Kidney failure
• Low platelet count (thrombocytopenia)
• Low red blood cell count (caused by the premature breakdown of red blood cells)
• Nervous system problems
• Severe bleeding (hemorrhage)