Sideroblastic Anaemia is a blood disorder in which the body has enough iron in the blood but is unable to use it to make haemoglobin. This results in accumulation of iron in the mitochondria of red blood cells. There are three categories of sideroblastic anaemias - inherited, acquired, and idiopathic (of unknown origin). The signs and symptoms can range from mild to severe, and include fatigue, breathing difficulties, and weakness. Enlargement of the liver or spleen may also occur.
HOW IS SIDEROBLASTIC ANEMIA DIAGNOSED?
A Cardiologist/Hematologist diagnoses Sideroblastic Anemia by ordering a complete blood count, and conducting MRI, bone marrow aspiration and liver biopsy. Also, the doctor carefully examines the history and clinical findings to accurately diagnose the cause of Sideroblastic Anemia.
HOW IS SIDEROBLASTIC ANEMIA TREATED?
Treatment depends on the cause of the sideroblastic anemia. Vitamin B6 (pyridoxine) therapy may be helpful in some cases. To remove excess iron from the body of someone with sideroblastic anemia, the drug desferrioxamine (Desferal) is infused under the skin (subcutaneously) or injected into a muscle (intramuscular), often with good results
DID YOU KNOW?
Some patients may not get relief from standard medications and as the problem tends to get worse, it could lead to complications and eventually death.