Polycythemia Vera is a rare disorder that is caused in the blood due to malfunctioning of a gene called JAK2. It is a condition that develops over long years and not in a sudden spurt. Polycythemia Vera is described as a form of cancer where the red blood cells count in the body grows beyond limits. Some mild symptoms like dizziness may be noticed, but in many cases, blood tests reveal the anomaly.
HOW IS POLYCYTHEMIA VERA DIAGNOSED?
There are many ways to diagnose Polycythemia Vera. Apart from the physical examination and asking a few questions on the symptoms being observed, the General Physician will ask for a complete blood count test being done. In some cases a bone marrow biopsy can also be done.
HOW IS POLYCYTHEMIA VERA TREATED?
Treatment focuses on reducing your amount of blood cells. In many cases, treatment can prevent complications from polycythemia vera and decrease or eliminate the disease's signs and symptoms.
Treatment may include:
• Taking blood out of your veins: Drawing a certain amount of blood out of your veins in a procedure called phlebotomy is usually the first treatment option for people with polycythemia Vera. This reduces the number of blood cells and decreases your blood volume, making it easier for your blood to function properly. How often you need phlebotomy depends on the severity of your condition.
• Low-dose aspirin: Your doctor may recommend that you take a low dose of aspirin to reduce your risk of blood clots. Low-dose aspirin may also help reduce burning pain in your feet or hands.
• Medication to decrease blood cells: For people with polycythemia Vera who aren't helped by phlebotomy alone, medications, such as hydroxyurea (Droxia, Hydrea), to suppress your bone marrow's ability to produce blood cells may be used. Interferon alpha may be used to stimulate your immune system to fight the overproduction of red blood cells.
• Therapy to reduce itching: If you have bothersome itching, your doctor may prescribe medication, such as antihistamines, or recommend ultraviolet light treatment to relieve your discomfort. Medications that are normally used to treat depression, called selective serotonin reuptake inhibitors (SSRIs), may be helpful in relieving itching. Examples of SSRIs include paroxetine (Paxil) or fluoxetine (Prozac).
DID YOU KNOW?
Polycythemia Vera occurs more often in men than in women and rarely in anyone under 40.