Maturity onset diabetes of the young (MODY) refers to any of several hereditary forms of diabetes caused by mutations in an autosomal dominant gene disrupting insulin production. MODY is more likely to affect adolescents and young adults, but it can occur at any age. Just like other forms of diabetes, MODY can cause complications throughout the body, including increased risk of heart and vascular disease, kidney disease, and blindness. Blood sugars will continue to rise, causing:
• Frequent urination
• Increased thirst
• Weight loss.
HOW IS MATURITY ONSET DIABETES OF THE YOUNG DIAGNOSED?
The diagnosis of MODY is done by:
• blood taken for pancreatic antibodies and blood or urine tested for C-peptide.
• blood taken for genetic testing.
HOW IS MATURITY ONSET DIABETES OF THE YOUNG TREATED?
Treatment is different for the different forms of MODY. Drugs from the oral sulfonylurea class are usually effective for patients with MODY 1, 3, and 4.Most of the patients will eventually need insulin to control their blood sugar levels. Insulin is generally taken by injection. MODY 2 rarely requires drug or insulin therapy, and can usually be managed by exercise and diet alone. MONDAY 5 may require several different treatments because it causes other problems in addition to diabetes.
DID YOU KNOW?
Maturity Onset Diabetes of the Young is a rare type of diabetes that is very different from Type I and Type II diabetes.