Lowe Syndrome is a condition that primarily affects the eyes, brain and kidneys. This disorder occurs almost exclusively in males. Infants with Lowe Syndrome are born with thick clouding of the lenses in both eyes, often with other eye abnormalities that can impair vision. About half of affected infants develop an eye disease called infantile glaucoma, which is characterized by increased pressure within the eyes. Many individuals with Lowe Syndrome have delayed development and intellectual ability ranges from normal to severely impaired. Behavioral problems and seizures have also been reported in children with this condition.
HOW IS LOWE SYNDROME DIAGNOSED?
Diagnosis by a pediatrician would reveal the same. These include tests like muscle movement and growth chart tracking, X-rays and scans along with blood tests.
HOW IS LOWE SYNDROME TREATED?
As the condition affects different body parts, there is a team of paediatric specialists needed to treat this condition. From a paediatric ophthalmologist, nephrologist, geneticist, nutritionist, endocrinologist, neurologist, child development specialist, general surgeon, to an orthopaedist and dentist will have to work in conjunction. Early removal of cataracts is recommended and use of eyeglasses is required for improving vision. Treatment of end-stage renal disease has been successfully treated with dialysis and kidney transplantation in some adult men.