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Liddle's syndrome is also known as Liddle syndrome and pseudohypoaldosteronism. This is basically an inherited form of genetic disorder that is again autosomal dominant. The common symptoms here include hypertension in children which is accompanied with low plasma renin and the blood potassium levels also go down. Alongside, weakness is also very common here.
HOW IS LIDDLE SYNDROME DIAGNOSED?
Evaluating a child with persistent high blood pressure requires testing of the blood electrolytes as well as aldosterone level. A genetic study of ENaC sequence can help in identifying the genetic mutations that can cause the condition.
HOW IS LIDDLE SYNDROME TREATED?
Treatment for this syndrome usually includes having a very low sodium diet and consuming potassium-sparing diuretic drugs to block the sodium from making the body pressure worse. For pregnant women, drugs like Amiloride are considered to be safe. Alongside other medications are also given to treat hypokalemia associated with this problem.
DID YOU KNOW?
Some individuals are not diagnosed with Liddle Syndrome until adulthood.