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LEUKOCYTE ADHESION DEFICIENCY
Leukocyte Adhesion Deficiency (LAD) is a rare autosomal recessive disorder that affects the immune system. Typically, there is a change in the way body reacts to a foreign invasion which normally happens in healthy individuals when white blood cells fight the disease causing microorganisms. The signs and symptoms vary largely from one person to another. Affected people usually have a higher count of white blood cells.
HOW IS LEUKOCYTE ADHESION DEFICIENCY DIAGNOSED?
Diagnosis by a haematology expert would be based on taking blood tests to check for preliminary tests of immune functions.
HOW IS LEUKOCYTE ADHESION DEFICIENCY TREATED?
The two main treatment modes here include intensive antibiotherapy along with granulocyte transfusions and finally the hematopoietic stem cell transplant, which is known as the most effective solution for combatting Leukocyte Adhesion Deficiency. Progress has also been made in gene therapy as an effective solution.
DID YOU KNOW?
The LAD is divided into three forms – LAD 1, LAD 2 and the recently described LAD 3. The LAD 1 is more common though the disease in itself is categorized as a rare disease.