Leiomyosarcoma is an aggressive soft tissue sarcoma derived from smooth muscle cells typically of uterine, gastrointestinal or soft tissue origin. Since smooth muscle is found all over the body, a Leiomyosarcoma can form almost anywhere where there are blood vessels, heart, liver, pancreas, genitourinary and gastrointestinal tract, the space behind the abdominal cavity (retroperitoneum), uterus, skin. The uterus is the most common location for a Leiomyosarcoma. General symptoms associated with cancer may occur including fatigue, fever, weight loss, a general feeling of ill health (malaise), and nausea and vomiting.
HOW IS LEIOMYOSARCOMA DIAGNOSED?
A diagnosis of a Leiomyosarcoma may be made based upon a detailed patient history, a thorough clinical evaluation and a variety of tests including blood tests, surgical removal and microscopic examination of tissue (biopsies) and various imaging techniques. Imaging techniques may include Computerized Tomography (CT) scanning, Magnetic Resonance Imaging (MRI) and ultrasound. During CT scanning, a computer and x-rays are used to create a film showing cross-sectional images of certain tissue structures.
HOW IS LEIOMYOSARCOMA TREATED?
Due to the rarity of these tumors, and the need for a multi-specialty treatment team, treatment is best carried out in a specialized center with expertise in sarcoma care. The usual treatment for a Leiomyosarcoma is, surgery to remove the tumour. Radiotherapy after surgery may be recommended to reduce the chance of cancer coming back. Chemotherapy is also sometimes used for a Leiomyosarcomas that has come back or that has spread.
DID YOU KNOW?
The cancer is rather resistant which means, it is not responsive to radiation or chemotherapy.