Glucocorticoid-remediable Aldosteronism is also called aldosterone synthase hyperactivity. Basically this is an autosomal dominant disorder where the body witnesses a drastic increase in aldosterone secretion - that is made by ACTH is no longer transient. There is an increase in plasma concentration and symptoms include fatigue, headaches, numbness, tingling sensation and also metabolic alkalosis.
HOW IS GLUCOCORTICOID-REMEDIABLE ALDOSTERONISM DIAGNOSED?
The diagnosis of the condition includes a blood test that will help in unravelling whether or not the patient is carrying the faulty gene. Also, the doctor will be able to detect the cause and extent of the damage with the help of a study of the symptoms. The doctor will also check the blood pressure and potassium levels.
HOW IS GLUCOCORTICOID-REMEDIABLE ALDOSTERONISM TREATED?
Treatment for Glucocorticoid-remediable Aldosteronism includes using medicines that manage hypersecretion of aldosterone by suppressing the ACTH secretion. Use of glucocorticoids, Dexamethasone, spironolactone and eplerenone are quite common for treating the issue.
DID YOU KNOW?
Although initially considered as a rare condition, the Glucocorticoid-remediable Aldosteronism is now regarded as one of the common causes of secondary hypertension in adults.