Colloid nodules, also known as adenomatous nodules or colloid nodular goiter are benign, a noncancerous enlargement of thyroid tissue. Although they may grow large, and there may be more than one, they are not malignant and they will not spread beyond the thyroid gland. Colloid nodules are the most common kind of thyroid nodule. Colloid nodules are usually small enough to be undetectable without an ultrasound or other imaging techniques. They usually produce no symptoms, so patients are unlikely to notice them until their size makes them easier to detect. Like other thyroid nodules, they are usually first noticed in a routine physical examination.
Thyroid enlargement -- may vary from a single small nodule to massive enlargement
1. Breathing difficulties from compression of the trachea (rare)
2. Swallowing difficulties from compression of the esophagus (rare)
3. Neck vein distention and dizziness when the arms are raised above the head (large goiter)
HOW IS COLLOID GOITRE DIAGNOSED?
Colloid nodules may be initially identified as an unspecified kind of thyroid nodule. Follow-up examinations typically include an ultrasound if it's unclear whether or not there really is a nodule present. Once the presence of a nodule has been confirmed, the determination of the kind of thyroid nodule is done by fine needle aspiration biopsy.
1. Thyroid scan
2. Thyroid ultrasound
3. Blood tests to monitor thyroid function including thyroid stimulating hormone (high if underactive, low if overactive)
4. Radioactive iodine uptake (normal or increased)
5. Urinary excretion of iodine (low)
HOW IS COLLOID GOITRE TREATED?
Thyroid hormone replacement therapy is prescribed for iodine deficiency. Hormone replacement inhibits thyroid stimulating hormone (TSH) and allows the thyroid to recover. A large goiter that is unresponsive to medical management or restricts swallowing and breathing may require partial or complete removal of the thyroid gland. If the goiter is producing too much thyroid hormone, treatment with radioactive iodine, antithyroid medication, or surgery may be necessary by an endocrinologist
DID YOU KNOW?
Colloid goitres occur between the ages of 20 and 50 and it is more common in women than in men.