Chronic Granulomatous Disease is a type of primary auto immune disorder that increases the infected person’s vulnerability to lose immunity to certain types of bacteria and fungi. The condition basically happens when the white blood cells in the body known as the phagocytes fail to fight common infections. People with this disorder are hence quite prone to pneumonia, lung infections, lymph infections, skin diseases and gastrointestinal issues. A recurrent bacterial and fungal infection is a clear indication of this condition.
HOW IS CHRONIC GRANULOMATOUS DISEASE DIAGNOSED?
The diagnosis of this condition can be carried out by the general physician who will conduct the NBT dye test as well as other lab tests involving the blood and urine in order to study the extent of the damage caused. Also, a blood cell count can help in diagnosing the issue along with a flow cytometric reduction test to find the carrier gene.
HOW IS CHRONIC GRANULOMATOUS DISEASE TREATED?
Treatment of chronic granulomatous disease consists of continuous antibiotic therapy to help prevent infections. Corticosteroid drugs are also of benefit for treating granulomatous complications. Bone marrow transplants have proven to be successful. Surgery may be needed to treat some abscesses. Genetic counseling may be of benefit for affected individuals and their families. Other treatment is symptomatic and supportive.
DID YOU KNOW?
People with CGD should avoid swimming except in chlorinated water to avoid infections as their immunity is very low.