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Alexander disease also known as fibrinoid leukodystrophy is a fatal neurological disease. It is very rare and genetic in nature. It mostly affects infants and children causing delayed developments in physical growth. The symptoms of this disease are: • Infantile Alexander Disease • Megalencephaly • Hydrocephalus: • Failure to thrive • Seizures: • Spasticity/spastic quadriparesis: • Progressive Psychomotor Retardation
HOW IS ALEXANDER DISEASE DIAGNOSED?
Diagnosis can be done through common tests conducted in neurology such as genetic testing of blood samples. Otherwise symptoms like large head size, or MRI scans can also be helpful.
HOW IS ALEXANDER DISEASE TREATED?
Symptomatic and supportive treatment may be done for Alexander disease. There is no cure for the disease at present
DID YOU KNOW?
Though Alexander disease is a genetic defect, it is not mandatory that it is genetically inherited also.