Alexander disease is an extremely fatal and rare, yet progressive neurological disorder in kids (also known as leukodystrophies) and mainly caused by defective mutation of genes. Symptoms include megalencephaly, hydrocephalus, failure to thrive, seizures, spastic quadriparesis, progressive psychomotor retardation, etc.
HOW IS ALEXANDER DISEASE DIAGNOSED?
Magnetic Resonance Imaging or an MRI Scan can help in detecting the problem. Usually, a Pediatric specialist will look into the case. Clinical examinations based on the symptoms and appearance of the patient, as well as radiological studies can also help in diagnosis of this disease.
HOW IS ALEXANDER DISEASE TREATED?
Treatment of Alexander disease is impossible as there is no cure for it. Water removal surgery from brain, bone marrow transplantation, etc. may be done but with no proven success rate.
DID YOU KNOW?
There are no more than 500 reported cases of Alexander disease in the world.