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Dr. Rajesh Ghagare

Cardiologist, Mumbai

300 at clinic
Dr. Rajesh Ghagare Cardiologist, Mumbai
300 at clinic  ·  ₹ online
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Personal Statement

My favorite part of being a doctor is the opportunity to directly improve the health and wellbeing of my patients and to develop professional and personal relationships with them....more
My favorite part of being a doctor is the opportunity to directly improve the health and wellbeing of my patients and to develop professional and personal relationships with them.
More about Dr. Rajesh Ghagare
Dr. Rajesh Ghagare is a trusted Cardiologist in Borivali East, Mumbai. You can visit him at Ashtavinayak Hospital in Borivali East, Mumbai. Save your time and book an appointment online with Dr. Rajesh Ghagare on Lybrate.com.

Find numerous Cardiologists in India from the comfort of your home on Lybrate.com. You will find Cardiologists with more than 25 years of experience on Lybrate.com. You can find Cardiologists online in Mumbai and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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1ST FLR, Goyal Trade Centre, Sona Theatre Blg, Borivali East, Landmark: Shantivan, MumbaiMumbai Get Directions
300 at clinic
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I had some sort of chest pain. I had done both ecg as well as 2d echocardiogram and both are normal. How long is the echocardiogram valid? Should I repeat this in case of persistent pain?

MBBS
General Physician
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I had some sort of chest pain. I had done both ecg as well as 2d echocardiogram and both are normal. How long is the ...
Dear lybrateyuser, - As your investigation results are normal your pain may not be of cardiac origin, could be due to acidity - avoid spicy, fried & junk food, chew your food well, do not skip meals, have meals on time, avoid more than 1-2 cups of tea, coffee per day, also alcohol, tobacco if you take, have dinner 2-3 hrs before bedtime - have 7-8 glasses of water per day - if it is more on exertion then do not strain, lift weight or do strenuous exercise - if pain is persistent then consult a doctor & take his advise.

I am having low sugar problem means low calories it is always difficult to eat calorie food what can I do?

PDDM, MHA, MBBS
General Physician
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Here is a sample diet for you. Breakfast - 1 glass banana milkshake+ 5 khajur+ 5 anjeer, •. Mid morning - 2 chikoo •. Lunch - 4 chapati + 1 bowl sabji+1 bowl dal++ 1 bowl rice + 1 bowl curd •tea time - tea + 1 pckt parleg •. Late evening - 1 bowl roasted chana •dinner same as lunch •. Bed time - 1 glass banana milkshake.

My friend suffered from suffocation and increased heart rate last night this thing occurred twice last week. He often feels weakness.

cc USG, MBBS
General Physician
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My friend suffered from suffocation and increased heart rate last night this thing occurred twice last week. He often...
It seems to be due to severe anxiety and this problem can be solved by meditation i can give you address of rajyoga meditation center near your house (this is free of cost) Consult privately for further management

Dengue Vaxia

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician
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Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

More information about dengvaxia - first vaccine against dengue

Sanofi awaits govt approval to launch dengue vaccine in india

Sanofi pasteur - dengue vaccine frequently asked questions
Dengue Vaxia

I have pain in my heart. What to do?

MBBS
General Physician
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I have pain in my heart. What to do?
Hello, Do you mean pain chest? CHEST PAIN in your case may be due to 1.acidity. 2. severe anxiety 3. muscular problem A. You can take Tablet Pantocid 40 mg one tablet before food for 3 days B. Local application of Volini gel 1% twice a day for 2-3 day you should go for BP check along with Base line ECG and review with report I am giving you some health tips to avoid acidity 1.Take small frequent meal kindly take 5-6 small meal in whole day 2.Take 6-8 glass of water in a day 4. Moderate physical activity regularly 5.avoid excessive tea, coffee 6. Do Not postpone Breakfast consult physician for further management

After bypass success heart surgery- life is normal but having pain in both side of chest left consolidated pain - any remedy-?

Certified Diabetes Educator, Registered Dietitian (RD), PGDD, Bachelor of Unani Medicine and Surgery (B.U.M.S), General Physician
Dietitian/Nutritionist
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Too much cholesterol in the blood can lead to cardiovascular disease. What you eat has a direct impact on your cholesterol level. In fact, a diet rich in fiber and other cholesterol-lowering foods may help lower cholesterol as much as statin medication for some people. Working with a registered dietitian and doctor is the key to develop and maintain a successful health program to manage it. I will inform you on how to make diet, lifestyle changes, make you understand instructions for taking medication because it won't work if you don't take it as directed. Consult privately for a holistic dietary therapy to solve your problems.

Sir I have high cholesterol. What should I do LIPID PROFILE, BASIC, SERUM (Spectrophotometry, Calculated) Cholesterol Total 287.00 mg/dL <200.00 Triglycerides 386.00 mg/dL <150.00 HDL Cholesterol 46.50 mg/dL >40.00 LDL Cholesterol 173.00 mg/dL <100.00 VLDL Cholesterol 67.50 mg/dL <30.00 Non-HDL Cholesterol 240.50 mg/dL <130.00.

MBBS, DNB (General Medicine), DNB Cardiology
Cardiologist
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Sir I have high cholesterol. What should I do
LIPID PROFILE, BASIC, SERUM
(Spectrophotometry, Calculated)
Cholesterol...
Cap Prelipids 1-0-1 for 12 weeks tab Roseday F 0-0-1 along with diet modification and life style modification.

What are the causes of high blood pressure? And what are the effects of it in our body?

Bachelor of Ayurveda, Medicine and Surgery (BAMS), MD - Ayurveda
Ayurveda
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What are the causes of high blood pressure? And what are the effects of it in our body?
Dear lybrate-user, high blood pressure is many times a symptom of underlying disease. You can visualize heart as a pump which is pumping blood (viscous liquid) across the body. It supplies the brain where it pumps against gravity. Similarly it also receives the blood from the legs which is again against gravity. In this closed circulation the blood vessels allow the gases like oxygen and carbondioxide and some liquid to pass through the membrane along with nutrients and waste products to and from various tissues. Blood pressure increases 1. The heart has to pump with higher intensity due to a blockage which restricts the blood supply to a critical organ including the brain and heart. 2. Blood vessels become narrow due to constriction or fat and calcified plaques deposited. 3. Certain hormones (chemicals) secreted by the kidneys and other organs cause the blood vessels to contract. 4. Stress which releases enzymes that increase blood pressure. 5. Electrolytes like sodium levels increase the osmotic pressure thereby increasing the volume of blood and thus blood pressure. It is mainly due to an underline endocrine disease. Considering these five points we need to investigate understand and try to address the cause by symptomatically managing the blood pressure. High blood pressure has multiple effects on to the body especially on small blood vessels which can burst (bleed) in brain, eyes and other organs. It also increases the risk of pushing a clot into the brain as well as damaging the blood vessel itself. The cholesterol and other lipids which circulate in the blood get pushed towards the walls of the vessel due to high blood pressure thereby increasing the risk of atherosclerosis. In short high blood pressure is a serious entity needs to be addressed objectively.

My wife age 42 years suffering from problem in respiration properly in some specific conditions. In high temperature and some times in tension she feels she can not breath properly and she can not breath with nostrils, she feels uneasy in this situation. What can be the problem. She also get up in a shock while in deep sleep if any body disturbs her sleep and cry in a very hostile manner. In a few seconds she get normal. We consult a neurologist but he say this is not a problem. Please guide what can be the problem. Is it heart related problem?

Diploma in Obstetrics & Gynaecology, MBBS
General Physician
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My wife age 42 years suffering from problem in respiration properly in some specific conditions. In high temperature ...
42 is perimenopausal time, means a few years before and after the periods stop at age ranging from 40-50 but women do live a healthy life till 100+with age related problems only. During this phase called menopausal syndrome the woman may suffer from either of these 5 symptoms / few of symptoms / none of symptoms. 1) periods stop & reproductive hormones decline and she is more prone to heart attacks 2) osteoporotic bones, hollow bones with less calcium 3) depression and empty nest syndrome as her own children are either married or leading their own lives and she feels unwanted 4) organs sag like skin shows some wrinkles, there is tendency to have urinary symptoms as bladder has less power in its muscles to retain urine for longer hours. 5) tendency to put on weight @ at least 1/2 kg per year. The woman can keep busy with her own hobbies and skills, she can continue to exercise & be careful about diet. Take supplements of calcium and vitamin d & multivitamins. Eat lots of fresh seasonal vegetables and fruits according to her constitution, drink toned milk & curds & reduce salt, sugar & fats. Get her checked for heart and bllod tested for lipids & sugar. Good to know that your own doctor has declared her as normal. Reassure her and this passing phase will be over soon.

I am suffering from pain left side lightly once my body was straight right move the chest pain was occurred. Please suggestions.

MBBS
General Physician
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I am suffering from pain left side lightly once my body was straight right move the chest pain was occurred. Please s...
It may be muscular pain take tab hifenac th 10 1 1 tab pantop 5 1 tab neurobion forte 15 1 1 1 avoid heighted pillow wake up early and do regular exercises neck and back exercises daily will help you.

Not making pressure in latrine take water more and more to do it please give me advice having gas trouble in chest headache and burning in chest not able to sit let gas come to chest and hurts so much my life is like hell if there is somebody please help me.

MD - Consultant Physician
Cardiologist
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Not making pressure in latrine take water more and more to do it  please give me advice having gas trouble in chest h...
Take 3 teaspoonful of esopgul every night problem will be solved. More roughage in meal like vegetable plenty may help.

Most of the people say that since cashews has high calorie and high saturated fat it is bad for cholesterol and diabetes people. Your expert opinion please.

PGP In Diabetologist, Fellowship in non-invasive Cardiology, MD - Medicine, MBBS
Endocrinologist
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Most of the people say that since cashews has high calorie and high saturated fat it is bad for cholesterol and diabe...
Not at all, all nuts are good for health if taken raw. New research from Louisiana State University found that people who regularly eat tree nuts — including almonds, macadamias, pistachios, walnuts, and cashews — have lower risks for Type 2 diabetes and heart disease. Their C-reactive protein (a major marker of inflammation) levels were lower. Their HDL (“good cholesterol”) levels were higher.

What is the function of heart in human body.

MBBS
General Physician
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What is the function of heart in human body.
Heart is a pump where one side is carrying impure blood and it sees to it that the impure blood is going to the lungs for purification and other side of the heart receives the purified blood and sends it to the whole body.

I am 22 years old and I am also a smoker I smoke from last 3 years and but from last 1 and a half year I feel that my heart is beating so fast sometimes my body gets shake and I feel a type of current in the whole body with teeth also what I will do Sir? please plz please answer.

MBBS
General Physician
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I am 22 years old and I am also a smoker I smoke from last 3 years and but from last 1 and a half year I feel that my...
Smoking kills is a right kind of advertising. Smoking (nicotine) is a stimulant which stimulates your heart to pump faster and forcefuly. Nicotine stimulates brain also. All you have to do is to stop smoking at once.

I have stomach ache with black stool since last two days. My ultra sound reports are ok. What should I do.

MBBS
General Physician
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I have stomach ache with black stool since last two days. My ultra sound reports are ok. What should I do.
you are having melena.it could be due to gastric ulcer.get your stool examined for occult blood and consult physician/gastroenterologist.you may have to do upper GI endoscopy

I want to increase my weight upto 50 kg. My diet is not proper and BP is also low due to stress. So pls guide me.

BAMS, MD Ayurveda
Ayurveda
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I want to increase my weight upto 50 kg. My diet is not proper and BP is also low due to stress. So pls guide me.
The best ayurveda herb for your case is Natural home remedy using figs and raisins: 1. Take 6 dried figs 2. Take 30 g raisins 3. Soak both in water overnight 4. Eat in 2 doses through the next day This will help with your concern, if it dosent work then you must consult ayurvedic doctor.

Chest pain recently and feeling something is stuck at my throat from last 1 month.

MS - ENT
Ear-Nose-Throat (ENT) Specialist
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Chest pain recently and feeling something is stuck at my throat from last 1 month.
Pain in throat may be due to allergy cum infection in throat. Through examination of throat is required. If required after taking throat swab for culture and sensitivity, accordingly antibiotics and antihistamincs, analgesics can be given.

My bp is 160/80 I take olmezest 40 and prolomet xl 25 diabetic metformin500 od hb1ac 6.1 lipid profile normal advice.

MD - General Medicine
General Physician
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My bp is 160/80 I take olmezest 40 and prolomet xl 25 diabetic metformin500 od hb1ac 6.1 lipid profile normal advice.
Keep a healthy lifestyle, exercise or walks, whatever suits you, proper home made food, fruits, no alcohol or smoking, that will be enough.
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