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Overview

Zymurine 50 MG Tablet

Manufacturer :  Zydus Cadila
Medicine Composition :  Azathioprine
Prescription vs OTC : Prescription by Doctor required

About Zymurine 50 MG Tablet

Zymurine 50 MG Tablet acts as an immuno-suppressant drug, which is used to treat ulcerative colitis, rheumatoid arthritis, Crohn's disease, and in kidney transplants to prevent the rejection of a new kidney. Zymurine 50 MG Tablet is also an anti-metabolite. It works by lowering the body's immune system against the transplanted kidney. Close monitoring of blood cell count is necessary while taking this medication so It should be used under the supervision of a qualified physician. It can be administered by mouth or injected into a vein.

Do not use this medicine if you are allergic to any ingredient in Zymurine 50 MG Tablet; if you are pregnant, if you have used alkylating agents in the past, or you are currently taking febuxostat or mercaptopurine. Inform your doctor if you have the following medical conditions to make sure this medicine will be safe for you :

  • kidney or liver disorders
  • bowel problems
  • a history of frequent, recurrent, or prolonged infection
  • scheduled to receive a vaccination or immunisation shortly.
  • a history of cancer, anaemia, bone marrow problems, unusual bruising or bleeding, or low white blood cell or platelet levels.
  • any enzyme deficiencies or recent blood transfusions.

Take this medication with food to reduce stomach upset. Dosage is as directed by your doctor, usually once or twice daily. The dosage is based on your weight, medical condition and response to treatment. If you increase your dose or use this drug more often or for longer than prescribed then you may increase the risk of it's side-effects.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Zymurine 50 MG Tablet

    • Kidney Transplantation

      Zymurine 50 MG Tablet is used in kidney transplant patients to prevent transplant rejection.

    • Rheumatoid Arthritis

      Zymurine 50 MG Tablet is used in the treatment of rheumatoid arthritis which is an inflammatory disease characerized by swelling, pain, and stiffness of joints.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Zymurine 50 MG Tablet ?

    • Allergy

      Not recommended in patients with known allergy to Zymurine 50 MG Tablet.

    • Alkylating agents

      Not recommended in patients with rheumatoid arthritis previously treated with cyclophosphamide, chlorambucil.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Zymurine 50 MG Tablet ?

    • Fever With Chills

    • Sore Throat

    • Abdominal Pain

    • Loss Of Appetite

    • Muscle And Joint Pain

    • Nausea Or Vomiting

    • Hair Loss Or Thinning Of The Hair

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Zymurine 50 MG Tablet

    • How long is the duration of effect?

      The duration of action of this medicine is not clinically established.

    • What is the onset of action?

      The effect of this medicine can be observed in 1 to 2 hours.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended in breastfeeding women.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Zymurine 50 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Zymurine 50 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      If you miss a dose of Zymurine 50 MG Tablet, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Zymurine 50 MG Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medication belongs to the class of an immunosuppressant drug. It works by lowering the production and expansion of T and B lymphocytes in the white blood cells which defends your body against foreign particles and infections.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Zymurine 50 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Warfarin

        This medicine may decrease the effect of warfarin. Inform the doctor if you are receiving either of the medications.Seek immediate medical treatment if you have any symptoms of breathing problem, blurred vision, blood clots and swelling of limbs.

        Angiotensin converting enzyme inhibitors

        These medications may lower the WBC count and may increase the risk of infections. Usage of antihypertensive medications like enalapril, ramipril, captopril should be reported to the doctor. Seek immediate medical treatment if you have any symptoms of infection like fever, chills, diarrhea, sore throat.

        Live attenuated vaccines and related products

        You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.
      • Interaction with Disease

        Disease

        Information not available.
      • Interaction with Food

        Food

        Information not available.

      References

      • Azathioprine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/azathioprine

      • Azathioprine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00993v

      • AZATHIOPRINE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=AZATHIOPRINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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