Varenicline

Varenicline, a nicotinic receptor partial agonist is used for treating nicotine addiction. It works by weakly stimulating the nicotine receptors than nicotine does itself. Being a partial agonist, it decreases the cravings as well as the pleasurable effects of cigarettes and other tobacco products and hence helps a patient to quit smoking.

Varenicline is available as capsular biconvex, white or blue film-coated tablets in two strengths i.e. 0.5 mg and 1 mg for oral administration. The preferable dosage of Varenicline is 1 mg twice daily and the course of medication follows 1 week titration. From day1 to day 3, 0.5 mg once daily, should be taken. From day4 to day day 7, 0.5 mg twice daily and from day 8 to the last day of treatment, 1 mg twice daily. Varenicline should be taken for at least 12 weeks. For those who have successfully completed the course of medication, an additional 12 weeks of treatment is advisable to help in long term abstinence.

Side effects of Varenicline include neuropsychiatric symptoms and suicidality, somnambulism, angioedema and hypersensitivity reactions, serious skin reactions, interaction with alcohol, accidental injury, seizures, cardiovascular events behaviour changes, laboured breathing, anxiety or restlessness and others.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Smoking Addiction

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Nausea

• Headache

• Insomnia (Difficulty In Sleeping)

• Abnormal Dreams

• Nasopharyngitis

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Is It safe with alcohol?

  Champix 1mg tablet may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  Champix 1mg tablet may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Varenicline, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which contains Varenicline as ingredient

• Champix 1Mg Tablet

  Pfizer Ltd

• Champix 0.5mg and 1mg Kit

  Pfizer Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Varenicline is an acetylcholine receptor partial agonist that is alpha-4 beta-2 neuronal nicotinic type. High selectivity for receptor subclass is determined by Varenicline. Varenicline brings about inhibition to nicotines ability to combine competitively.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.