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Overview

Tolbutamide

Prescription vs OTC : Prescription by Doctor required

About Tolbutamide

Tolbutamide is a potassium channel blocker and sulfonylurea oral hypoglycemic medicine used in the treatment of type 2 diabetes. This medication should be taken with proper diet and exercise as alone it is not sufficient to control diabetes.

It stimulates the secretion of natural insulin from the pancreas that helps lower blood sugar levels. The medicine should not be used if:

  • you have a condition of severe allergic reaction to it or any ingredient in it
  • you have diabetic coma or diabetic ketoacidosis, severe burns or acidosis
  • you are pregnant, plan on becoming pregnant, breastfeeding
  • you are taking any supplements, herbal preparations, or medicines
  • you have a history of any hormonal problem, kidney, heart, thyroid or liver problem, or have stomach paralysis, blockage, alcohol addiction, have any medical condition or poor nutrition

This medicine is taken by mouth with food. It is recommended that you take it once every day on a regular basis as per the dosage prescribed by the doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the uses of Tolbutamide

    • Type 2 Diabetes

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the side effects of Tolbutamide ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    Key highlights of Tolbutamide

    • Are there any pregnancy warnings?

      This medication may be unsafe to use during pregnancy.

    • Are there any breast-feeding warnings?

      This medication is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Vision may be affected with this. Exercise caution if you have to drive or operate a machinery.

    • Does this affect kidney function?

      Should be used cautiously in patients with an underlying kidney disease. Please consult your doctor.

    • Does this affect liver function?

      Should be used cautiously in patients with an underlying liver disease. Please consult your doctor.

    • How long is the duration of effect?

      The duration of effect of this medication when taken orally is 6-24 hours while if it is administered intravenously the duration of effects is 3 hours.

    • What is the onset of action?

      The onset of action orally is 1-3 hours while intravenously it is 30 minutes.

    • Is it habit forming?

      No habit forming tendencies are found.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    Medicines containing Tolbutamide

    Below is the list of medicines, which contains Tolbutamide as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    How does this medication work?

    This medication lowers blood glucose within patients. It directly stimulates the release of insulin from the functioning of beta cells of the pancreatic islet tissue. It involves a method comprising sulfonylurea receptor acting on the beta-cell.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

      What are the interactions of Tolbutamide ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medicine interacts with the following medicine which include beta-blockers, cholestyramine, hydantoins, thiazides, and rifampin.

      FAQs about Tolbutamide

      • Ques : What is Tolbutamide?

        Ans : This medication is a potassium channel blocker and sulfonylurea oral hypoglycemic medicine used in the treatment of type 2 diabetes.

      • Ques : How long do I need to use Tolbutamide before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Tolbutamide?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Tolbutamide empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Tolbutamide?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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