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Overview

Terbutaline

Prescription vs OTC : Prescription by Doctor required

About Terbutaline

Terbutaline works as a bronchodilator in reversible airway obstruction and bronchial asthma. Use exactly as directed (see Administration below). Do not use more often than recommended (excessive use may result in tolerance, overdose may result in serious adverse effects) and do not discontinue without consulting prescriber.

Being a bronchodilator, Terbutaline works by relaxing the muscles around the bronchioles in the lungs and opening them up. This helps air to pass in and out easily of the lungs. It is useful to treat spasms or contractions of the bronchioles, seen in asthma, bronchitis and emphysema.

It is not to be used if you are allergic to any of its ingredients or to a sympathomimetic amine like epinephrine and albuterol. Let your doctor know if you are pregnant or breastfeeding. While beta blockers may decrease its effectiveness, insulin’s effectiveness is decreased if taken along with this drug.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). You may experience nervousness, dizziness, or fatigue (use caution when driving or engaging in tasks requiring alertness until response to drug is known); or dry mouth, stomach upset (frequent small meals, frequent mouth care, chewing gum, or sucking hard candy may help).

Report unresolved GI upset; dizziness or fatigue; vision changes; chest pain, rapid heartbeat, or palpitations; insomnia, nervousness, or hyperactivity; muscle cramping, tremors, or pain; unusual cough; or rash (hypersensitivity).

Self-administered inhalation: Store canister upside down; do not freeze. Shake canister before using. Sit when using medication. Close eyes when administering terbutaline to avoid spray getting into eyes.

Exhale slowly and completely through nose; inhale deeply through mouth while administering aerosol. Hold breath for 1-3 seconds after inhalation. Wait at least 1 full minute between inhalations.

Wash mouthpiece between use. If more than one inhalation medication is used, use bronchodilator first and wait 5 minutes between medications. Symptoms of overdose include seizures, nausea, vomiting, tachycardia, cardiac dysrhythmias, hypokalemia.

In cases of overdose, supportive therapy should be instituted; prudent use of a cardioselective beta-adrenergic blocker (eg, atenolol or metoprolol) should be considered, keeping in mind the potential for induction of bronchoconstriction in an asthmatic individual. Dialysis has not been shown to be of value in the treatment of an overdose with this agent.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the uses of Terbutaline

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the contraindications of Terbutaline ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the side effects of Terbutaline ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Key highlights of Terbutaline

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Pregnant women must consult doctor before using this medication.

    • Are there any breast-feeding warnings?

      Breastfeeding women should consult doctor before taking Terbutaline.

    • Is it safe to drive while on this medicine?

      This medicine usually does not affect the patients consciousness or their ability to drive.

    • Does this affect kidney function?

      Caution must be taken while using this medicine in patients with kidney disease. Adjustment of dose is needed.

      • Clcr 10-50 mL/minute: Administer at 50% of normal dose.
      • Clcr <10 mL/minute: Avoid use.
      Kindly consult with your doctor before taking it.

    • Does this affect liver function?

      Limited information is available regarding its use in patient with liver disease. Kindly consult with your doctor before taking it.

    • How long is the duration of effect?

      The effect of this medicine remain active for about 11 - 16 hours.

    • What is the onset of action?

      The effect of this drug is initiated within 30 - 45 minutes after its administration.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

    • Are there any overdose instructions?

      Consult your doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Medicines containing Terbutaline

    Below is the list of medicines, which contains Terbutaline as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    How does this medication work?

    Thisn medication causes pharmacological effects. This is assigned to stimulation via beta-adrenergic receptors of the intracellular adenylyl cyclase. The intracellular adenyl cyclase enzyme causes conversion of adenosine triphosphate into adenosine monophosphate.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

      What are the interactions of Terbutaline ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Medicine

        • Decreased effect with beta-blockers
        • Increased toxicity with MAO inhibitors, TCAs
      • Interaction with Disease

        Excessive or prolonged use may lead to tolerance; paradoxical bronchoconstriction may occur with excessive use; if it occurs, discontinue terbutaline immediately.

      FAQs about Terbutaline

      • Ques : What is Terbutaline?

        Ans : Terbutaline is a salt which performs its action by calming the muscles in the air passages and widens airways. This makes breathing easier.

      • Ques : What are the uses of Terbutaline?

        Ans : Terbutaline is a salt which is used for the treatment and prevention from conditions such as Acute asthma and Asthma - Maintenance.

      • Ques : What are the Side Effects of Terbutaline?

        Ans : Side effects include headache, dizziness, sweating, drowsiness and others.

      • Ques : What are the instructions for storage and disposal Terbutaline?

        Ans : Terbutaline should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

      References

      • Terbutaline-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 11 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/terbutaline

      • Terbutaline-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 11 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00871

      • TERBUTALINE injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 11 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=TERBUTALINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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