Ruxolitinib

Ruxolitinib is a type of kinase inhibitor used to treat bone marrow problems like myelofibriosis and polycythemia vera in case there is an inadequate response or intolerance towards hydroxyurea. Its mechanism involves blocking substances involved in myelofibriosis, like JAK1 and JAK2.

It is advised that you should not use Ruxolitinib if you have allergy to it or any other ingredient used in it, or have any serious infection. You should also first consult a doctor before taking it if you are pregnant, plan on becoming pregnant, or breastfeeding, on dialysis, taking any supplements, medication or herbal preparations, or have low white blood cells or low blood platelet count, anemia, or a history of liver problems, kidney problems, or skin cancer.

The side effects you may encounter after taking Ruxolitinib includes diarrhoea, constipation, gas, dizziness, headache, stomach pain, muscle spasm, weight gain, tiredness. You should see a doctor if any of these become bothersome. If you develop any severe allergic reactions like rashes, itching, hives, difficulty in breathing, swelling of lips, tongue, mouth or throat then you should immediately visit a dcotor.

Ruxolitinib is available as 5mg, 10mg, 15mg, 20mg, and 25mg tablets that is to be taken orally. You can take them with or without food once every day but it is recommended that you should consult a doctor for appropiate dosage and should take this medication only if prescribed by the doctor.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Allergist/Immunologist before using this medicine.

• Headache

• Dizziness

• Reduced Blood Platelets

• Bruise

• Anemia

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Allergist/Immunologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Jakavi 20mg tablet may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Jakavi 20mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.

• Does this affect kidney function?

  Caution should be used in patients with renal impairment.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Allergist/Immunologist before using this medicine.

Below is the list of medicines, which contains Ruxolitinib as ingredient

• Jakavi 20Mg Tablet

  Novartis India Ltd

• Jakavi 15Mg Tablet

  Novartis India Ltd

• Jakavi 5Mg Tablet

  Novartis India Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Allergist/Immunologist before using this medicine.

This medicine, being a Janus kinase inhibitor, blocks disarticulated JAK signalling, that might result in myelofibrosis.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Allergist/Immunologist before using this medicine.