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Overview

Ranitidine 150 MG Tablet

Banned
Manufacturer :  Jagsonpal Pharmaceuticals Ltd
Medicine Composition :  Ranitidine
Prescription vs OTC : Prescription by Doctor not required

About Ranitidine 150 MG Tablet

Ranitidine 150 MG Tablet is prescribed as the short-term treatment of active duodenal ulcers and benign gastric ulcers. This medicine is also prescribed for long-term prophylaxis of duodenal ulcer and gastric hypersecretory states, recurrent postoperative ulcer, prevention of acid-aspiration pneumonitis during surgery, and prevention of stress-induced ulcers; causes fewer interactions than cimetidine.

This medicine belongs to a drug group known as histamine (H2) receptor blocker. Ranitidine 150 MG Tablet works by reducing the amount of acid produced in the stomach, effectively treating gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome and upper GI bleeding ulcers.

Patients need to be aware that intake of this medicine can increase the chances of succumbing to pneumonia. Its symptoms are pain in the chest, fever, coughing up slimy green snot and problems with breathing. Also, make sure that you are not allergic to this medication.

Make sure it is safe for you to consume this medication if you suffer from health problems like liver, kidney disease and porphyria. Although this medication does not really harm an unborn child, ensure that you tell your doctor if you are pregnant.

This medicine does pass into breast build, thus let your doctor know if you are taking this medication while breastfeeding too. It should be taken according to instructions given by the doctor. Do not change the dosage on your own.

This medication is meant for oral consumption and should be swallowed immediately. Do not chew or let the effervescent tablet dissolve after you place it in your mouth.

For instance, if you are taking 25 mg of it, dissolve it in 1 teaspoon of water. If you are taking 150 mg of this medicine, it should be dissolved in 6-8oz of water. It should be continued until the ulcer heals completely. Generally, it takes about 8 weeks for an ulcer to properly heal.

Take exactly as directed (at meals and bedtime); do not increase dose - may take several days before you notice relief. If antacids are approved by prescriber, allow 1 hour between antacid and Ranitidine 150 MG Tablet.

Avoid OTC medications, especially cold or cough medication and aspirin or anything containing aspirin. Follow the diet as the prescriber recommends.

Symptoms of overdose include muscular tremors, vomiting, rapid respiration, renal failure, CNS depression. Treatment is primarily symptomatic and supportive.

Use with caution in children <12 years of age; use with caution in patients with liver and renal impairment; dosage modification required in patients with renal impairment; long-term therapy may cause vitamin B12 deficiency.

    What are the uses of Ranitidine 150 MG Tablet

    • Duodenal Ulcer

    • Gastric Ulcer

    • Gastroesophageal Reflux Disease

    • Erosive Esophagitis

    • Zollinger-Ellison Syndrome

    • Hypersecretory Condition

    • Other Forms Of Ulcers

    What are the contraindications of Ranitidine 150 MG Tablet ?

    • Hypersensitivity

      This medication is not recommended for use in patients who have a known history of allergy to Ranitidine (the primary constituent of Ranitidine) or any other component of the medicine.

    What are the side effects of Ranitidine 150 MG Tablet ?

    Key highlights of Ranitidine 150 MG Tablet

    • How long is the duration of effect?

      The effect of this medication lasts for an average duration of 6 - 8 hours.

    • What is the onset of action?

      The effect of this medication can be observed after an hour of oral administration.

    • Are there any pregnancy warnings?

      Caution is advised while using this medicine during pregnancy. You should consult a doctor and use this medication only if the benefits outweigh the risks associated.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      Caution is advised while using this medicine during pregnancy. You should consult a doctor and use this medication only if the benefits outweigh the risks associated.

    • Does this affect kidney function?

      Dose adjustment is advised in the patient with renal impairment.

    • Does this affect liver function?

      No information regarding dose adjustment is available in hepatic patients.

    • Is It safe with alcohol?

      It is suggested not to take Ranitidine 150 MG Tablet with alcohol, as it is unsafe to take it concomitantly.

    • Is it safe to drive while on this medicine?

      Driving is usually safe if you are taking Ranitidine 150 MG Tablet. As this medicine does not affect patients ability to drive.

    What are the substitutes for Ranitidine 150 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Ranitidine 150 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.

    • Are there any overdose instructions?

      Contact a doctor immediately if an overdose is suspected.

    How does this medication work?

    This medication acts by inhibiting the action of histamine at specific H2 receptors present in the gastric parietal cells. Thus, gastric acid secretion process is inhibited. Thus, gastric volume and hydrogen ion concentration reduced.

      What are the interactions of Ranitidine 150 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Avoid the consumption of alcohol while taking this medicine. Contact your doctor if you experience prolonged heartburn or presence of blood in the vomit or stools.
      • Interaction with Lab Test

        False-positive urine protein, gastric acid secretion test, skin test allergen extracts, serum creatinine and serum transaminase concentrations, urine protein test might appear. Thus before testing must inform your doctor that you are taking Ranitidine 150 MG Tablet
      • Interaction with Medicine

        • Ketoconazole: Report the use of either of the medicine to the doctor. The use of this medication tends to make Ketoconazole less effective. Inform the doctor if the symptoms do not improve or worsen. Do not discontinue the use of any medicine without consulting your doctor.
        • Loperamide: Report the use of either of the medicine to the doctor. Dose adjustment and safety monitoring may be needed when both these medicines are taken together. Your doctor may prescribe alternative medicine if your intake of Loperamide is very high or you suffer have a heart condition.
        • Metformin: Report the use of either of the medicine to the doctor. An adjustment in dose and more frequent monitoring of blood level are advised when these two medicines are taken together.
        • Atazanavir: Report the use of either of the medicine to the doctor. Your doctor may adjust the dosage of Atazanavir when it is to be consumed along with this medication. Do not stop the usage of any medication without consulting your doctor.
        • Dasatinib: Report the usage of either of the medications to the doctor. It is advised to replace one or both of these medicines with alternates that do not interact. Do not stop the usage of any medication without consulting the doctor.
        • Pazopanib: Report the use of either of the medicine to the doctor. Use of these two medications together should be avoided. Your doctor may prescribe suitable alternatives in such cases.
        • Decreased toxicity of atropine.
        • Increased toxicity of cyclosporine (increased serum creatinine), gentamicin (neuromuscular blockade), glipizide, glyburide, midazolam (increased concentrations), metoprolol, pentoxifylline, phenytoin, quinidine.
      • Interaction with Disease

        • Gastrointestinal Bleeding: Use of this medication is not recommended for use if any symptoms indicating gastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.
        • Porphyria: This medication should be used with extreme caution in patients having a history of acute Porphyria.

      FAQs about Ranitidine 150 MG Tablet

      • Ques : What is Ranitidine 150 MG Tablet?

        Ans : The medication belongs to a drug group known as histamine-2 blocker. It reduced the amount of acid production in the stomach, effectively treating stomach and intestine ulcers.

      • Ques : How long do I need to use Ranitidine 150 MG Tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition.

      • Ques : At what frequency do I need to use Ranitidine 150 MG Tablet?

        Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

      • Ques : Should I use Ranitidine 150 MG Tablet empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      • Ques : What are the instructions for the storage and disposal of Ranitidine 150 MG Tablet?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children.

      • Ques : Is Ranitidine 150 MG Tablet banned?

        Ans : Food and Drug Administration (FDA), in 2020, requested that all forms of prescription & OTC ranitidine (Zantac) should be removed from the U.S. market.

      • Ques : Why is Ranitidine 150 MG Tablet banned?

        Ans : This recommendation was made because unacceptable levels of NDMA, a probable carcinogen (cancer-causing chemical), were found. If you’re prescribed this medication then you must talk to your doctor about safe alternative options.

      • Ques : Is Ranitidine 150 MG Tablet an antacid?

        Ans : No. This medication works by reducing the amount of acid your stomach makes. Whereas, antacids neutralize the acid that your stomach has already made.

      • Ques : How long does it take for Ranitidine 150 MG Tablet to start working?

        Ans : This medication starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.

      • Ques : Can I consume alcohol with Ranitidine 150 MG Tablet?

        Ans : Alcohol does not interfere with the working of Ranitidine 150 MG Tablet. But, you should avoid taking alcohol as it may further damage the stomach, delaying your recovery.

      • Ques : What are the serious side effects of Ranitidine 150 MG Tablet?

        Ans : Some of the serious side effects include hives, skin rash, itching, hoarseness and difficulty in breathing or swallowing.

      • Ques : Is Ranitidine 150 MG Tablet safe for long-term use?

        Ans : There is limited data available on whether Ranitidine 150 MG Tablet can be used for the long term or not, but it is a relatively safe medicine. It is advised to consume Ranitidine 150 MG Tablet for the duration prescribed by your doctor.

      • Ques : Is Ranitidine 150 MG Tablet effective?

        Ans : This drug would be effective only if used for the right indication in the dose and for the duration as advised by the doctor. It is advised to not to change the dose or stop consuming the drug without consulting your doctor.

      References

      • Ranitidine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/66357-35-5

      • Zantac Tablets 150mg- EMC [Internet]. www.medicines.org.uk. 2015 [Cited 25 April 2019]. Available from:

        https://www.medicines.org.uk/emc/product/219/smpc

      • Ranitidine: Uses, Side effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

        https://www.drugsbanks.com/ranitidine/

      • RANITIDINE - ranitidine hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2012 [Cited 25 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c79c92e0-1e7b-4854-a99a-1a22eed3c333

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Jagdish Prasad MehrotraD.P.H, MBBSGeneral Physician
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