PENTOREL 0.3MG/ML INJECTION

The primary use of this medicine is for the management of moderate to severe pain. PENTOREL 0.3MG/ML INJECTION falls under a category of drugs called opioid agonist-antagonists. It is given to people with an addiction or dependence on opioiods. It is used to cure drug abuse. It functions by preventing the withdrawal symptoms caused by drug abuse.

On using PENTOREL 0.3MG/ML INJECTION you may experience side effects such as dizziness, drowsiness, headache, sedation, nausea, fatigue, headache, xerostomia, hyperhidrosis, vomiting, sweating, fever, irregular heartbeat and difficulty in breathing. If the allergic reactions become severe, seek medical attention right away.

Before taking PENTOREL 0.3MG/ML INJECTION inform your doctor of the following conditions, if you have-

• Any allergies,
• Any brain disorders
• Liver/stomach/mental disorders,
• Diarrhea, constipation, or any infection,
• Problems urinating,
• Pregnant or are planning to become pregnant or are breastfeeding.

PENTOREL 0.3MG/ML INJECTION comes as a sublingual tablet, transdermal film and injectable solution. Dosage should be recommended by the doctor based on your condition. The usual dosage in adults for narcotics addiction is about 8 mg sublingually on day 1 and 16 mg on day 2. In case of drug overdose notify your doctor immediately.

Symptoms of overdose include CNS depression, pinpoint pupils, hypotension, bradycardia. Treatment of an overdose includes support of the patient's airway, establishment of an I.V. line, and administration of naloxone 2 mg I.V. (0.01 mg/kg for children) with repeat administration as necessary up to a total of 10 mg.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Pain

• Opioid (Morphine) Dependence

• Moderate To Severe Pain

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Hypersensitivity

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Headache

• Dizziness

• Vomiting

• Sleepiness

• Nausea

• Respiratory Depression

• Hypotension

• Slurred Speech

• Confusion

• Nervousness

• Depression

• Pruritus

• Constipation

• Urinary Retention

• Blurred Vision

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Is It safe with alcohol?

  This medicine may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  PENTOREL 0.3MG/ML INJECTION may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

• What is the onset of action?

  The effect is initiated within 10-30 minutes after its administartion.

• How long is the duration of effect?

  The duration of this medicine is about 6 to 8 hours.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

Below is the list of medicines, which have the same composition, strength and form as PENTOREL 0.3MG/ML INJECTION , and hence can be used as its substitute.

• BUPRINOR 0.3MG/ML INJECTION

  Astra Zeneca

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Buprenorphine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

This medication falls under the category of an opioid drug that works by triggering opioid receptors in the body to provide relief from pain. It combines with the brain receptors which are responsible for opioid intoxication. This drug binds easily with the receptors and acts as a replacement for stronger opioids like heroin and morphine.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  • Barbiturate anaesthetics may produce additive respiratory and CNS depression.
  • Respiratory and CV collapse was reported in a patient who received diazepam and PENTOREL 0.3MG/ML INJECTION

• Interaction with Disease

  • May cause respiratory depression - use caution in patients with respiratory disease or pre-existing respiratory depression.
  • Potential for drug dependency exists, abrupt cessation may precipitate withdrawal.
  • Use caution in elderly, debilitated, or pediatric patients.
  • Use with caution in patients with depression or suicidal tendencies, or in patients with a history of drug abuse.
  • Tolerance, psychological and physical dependence may occur with prolonged use.
  • Use with caution in patients with hepatic, pulmonary, or renal function impairment.
  • May cause CNS depression, which may impair physical or mental abilities.
  • Patients must be cautioned about performing tasks which require mental alertness (ie, operating machinery or driving).
  • Effects with other sedative drugs or ethanol may be potentiated.
  • Elderly may be more sensitive to CNS depressant and constipating effects.
  • Use with caution in patients with head injury or increased ICP, biliary tract dysfunction, pancreatitis, patients with history of ileus or bowel obstruction, glaucoma, hyperthyroidism, adrenal insufficiency, prostatic hypertrophy, urinary stricture, CNS depression, toxic psychosis, alcoholism, delirium tremens, or kyphoscoliosis.
  • Partial antagonist activity may precipitate acute narcotic withdrawal in opioid-dependent individuals.

• Ques : What is PENTOREL 0.3MG/ML INJECTION?

  Ans : PENTOREL 0.3MG/ML INJECTION is a type of agonist-antagonists. It is prescribed to patients who have an addiction or dependence on opioids.

• Ques : What are the uses of PENTOREL 0.3MG/ML INJECTION?

  Ans : PENTOREL 0.3MG/ML INJECTION is used to treat Pain and Opioid (Morphine) Dependence.

• Ques : What are the side effects of PENTOREL 0.3MG/ML INJECTION?

  Ans : Side effects of this drug include Headache, Dizziness, Vomiting, Sleepiness, Nausea and Constipation.

• Ques : Is PENTOREL 0.3MG/ML INJECTION an opiate/ opiate blocker/ controlled substance/ painkiller/ addictive?

  Ans : PENTOREL 0.3MG/ML INJECTION comes under the category of agonist-antagonists. It helps in relieving pain. This drug can be addictive and hence consult your doctor if you experience addiction to this drug.

• Ques : Does PENTOREL 0.3MG/ML INJECTION block opiates?

  Ans : PENTOREL 0.3MG/ML INJECTION helps in blocking opiates. It is used to treat Opioid dependence.

• Ques : Can PENTOREL 0.3MG/ML INJECTION cause depression?

  Ans : This drug does not cause depression or anxiety. If you experience such side effects, then consult a doctor as soon as possible.

• Buprenorphine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/buprenorphine

• Buprenorphine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

  https://go.drugbank.com/drugs/DB00921

• BUPRENORPHINE injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=BUPRENORPHINE