Lybrate Logo
Get the App
For Doctors
Login/Sign-up
tab_logos
About
tab_logos
Feed
Overview

Onset 4 MG Tablet

Manufacturer :  Intas Pharmaceuticals Ltd
Medicine Composition :  Ondansetron
Prescription vs OTC : Prescription by Doctor required

About Onset 4 MG Tablet

Onset 4 MG Tablet is prescribed for the treatment of nausea as well as vomiting, caused by other medical treatments such as surgery, chemotherapy and radiation. This belongs to the antiemetics class of drugs. This medicine work by blocking the chemical serotonin from releasing in your gut and your central nervous system. This will prevent vomiting and nausea.

Onset 4 MG Tablet is available in four different forms that can be taken orally; tablet, disintegrating (dissolving) tablet, solution and film. It also comes in an IV (intravenous) form that can be injected to your body by a doctor. You can take it with food or without food.

This medicine can be used alone as well as in a combination with other medicines for preventing vomiting and nausea that one experiences after a surgery, chemotherapy or radiation session.

Your doctor must be informed if you are allergic to Onset 4 MG Tablet as well as other medications that block serotonin, along with any other allergies that you have. He/ She must also know about your medical history and if you had problems such as:

Apart from that, you must also inform the doctor if you are under any medication for depression or any psychiatric disorder. The dosage of Onset 4 MG Tablet is decided after taking your medical condition into account and how responsive your body is to therapy. In the case of children, the dose also depends on their weight and age.

If you are undergoing chemotherapy, you need to take Onset 4 MG Tablet orally half an hour before your treatment starts. In case of radiation, take it 1-2 hours before the procedure of treatment begins. For preventing nausea before surgery, it is advised to take the medication an hour before your surgery.

In case you miss a dose, you can take the medication once you remember it. If it is already time for the next dose, ensure that you do not take two doses to make up for the missed dose. Overdose of Onset 4 MG Tablet can lead to severe constipation, faint spells or feeling light-headed.

The side effects of Onset 4 MG Tablet can include dizziness, drowsiness, diarrhea, constipation and headache. These side effects are usually mild in nature and go away in a few days or 1-2 weeks. You can consult your doctor if these symptoms remain for a long time. There are some serious side effects that Onset 4 MG Tablet may have, which would require immediate medical supervision.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Onset 4 MG Tablet

    • Nausea Or Vomiting

      Onset 4 MG Tablet is used to treat nausea and vomiting.

    • Nausea

      Onset 4 MG Tablet is used to treat nausea and vomiting in cancer chemotherapy patients.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Onset 4 MG Tablet ?

    • Allergy

      Avoid if the patient has a known allergy to Onset 4 MG Tablet.

    • Apomorphine

      Avoid using Onset 4 MG Tablet with Onset 4 MG Tablet as it increases the risk of lightheadedness and loss of consciousness.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Onset 4 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Onset 4 MG Tablet

    • How long is the duration of effect?

      This medicine is excreted primarily in urine and the effect of this medicine lasts for a duration of 12 to 28 hours.

    • What is the onset of action?

      The peak effect of Onset 4 MG Tablet can be observed within 30 minutes for Intravenous and 2 hours for the tablet.

    • Are there any pregnancy warnings?

      Use of Onset 4 MG Tablet is not recommended in pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      No clear data is available whether Onset 4 MG Tablet is excreted through human breast milk. So, use of this drug is not recommended in breastfeeding women.

    • Is It safe with alcohol?

      It is safe to consume alcohol along with Onset 4 MG Tablet.

    • Is it safe to drive while on this medicine?

      Onset 4 MG Tablet does not usually affect patients ability to drive.

    • Does this affect kidney function?

      It is found safe to use Onset 4 MG Tablet in patients with kidney disease. No adjustment of dose is needed.

    • Does this affect liver function?

      Limited information for Onset 4 MG Tablet is available in patients with liver disease. kindly consult your doctor before taking this medicine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Onset 4 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Onset 4 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical attention or contact the doctor in case of overdose.

    • Are there any missed dose instructions?

      Take the missed dose as soon as possible and avoid taking it if its almost time for the other dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Onset 4 MG Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medication works peripherally and centrally by blocking 5-HT3 receptors present on vagal nerve terminals and CTZ respectively.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Onset 4 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Onset 4 MG Tablet causes hypokalemia, thus monitoring of potassium serum concentration is recommended.
      • Interaction with Medicine

        Apomorphine

        Use of Onset 4 MG Tablet with Apomorphine is not recommended. Replacement of the drug should be considered under the doctor's supervision. Usage of other medicines should be reported to the doctor.

        Amiodarone

        Use of Onset 4 MG Tablet with Amiodarone is not recommended as it may cause dizziness, lightheadedness, difficulty in breathing if these drugs are used together. Regular cardiac function tests are to be performed if the patient is having any heart disease. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

        Amitriptyline

        If these drugs are used together, the patient may experience confusion, hallucination, changes in blood pressure, fever or excessive sweating. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

        Carbamazepine

        Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

        Phenytoin

        Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

        Cyclophosphamide

        The desired effect of cyclophosphamide will not be obtained if these drugs are concurrently taken. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
      • Interaction with Disease

        Qt Prolongation

        Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.

        Liver Disease

        Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.
      • Interaction with Food

        Information not available.

      FAQs about Onset 4 MG Tablet

      • Ques : How quickly does Onset 4 MG Tablet work?

        Ans : This drug starts working within 30 minutes to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

      • Ques : What are the side effects of Onset 4 MG Tablet?

        Ans : Side effects include constipation, diarrhea, fatigue and headache. It is advised to consult your doctor if these symptoms stay for a longer time.

      • Ques : When should you take Onset 4 MG Tablet?

        Ans : This medication must be taken with a glass of water. You can consume it with or without food. It should be used exactly as per the dose and duration advised by the doctor.

      • Ques : Is Onset 4 MG Tablet a steroid?

        Ans : No, this medication is an anti-emetic and not a steroid.

      • Ques : Does Onset 4 MG Tablet work for seasickness?

        Ans : No, it does not work for seasickness. This is because Ondansetron has little effect on nausea associated with motion sickness.

      References

      • Ondansetron- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 3 December 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ondansetron

      • Ondansetron 4mg Orodispersible Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 3 December 2021]. Available from:

        https://www.medicines.org.uk/emc/product/10164/smpc

      • Important Information About Ondansetron- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 3 December 2021]. Available from:

        https://www.drugsbanks.com/important-information-about-ondansetron/

      • ONDANSETRON- ondansetron hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2011 [Cited 3 December 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fc3d39e0-8bf2-4c29-b872-66a1cf8bb2fb

      • Ondansetron- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 3 December 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ondansetron

      • Ondansetron 4mg Orodispersible Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 3 December 2021]. Available from:

        https://www.medicines.org.uk/emc/product/10164/smpc

      • Important Information About Ondansetron- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 3 December 2021]. Available from:

        https://www.drugsbanks.com/important-information-about-ondansetron/

      • ONDANSETRON- ondansetron hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2011 [Cited 3 December 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fc3d39e0-8bf2-4c29-b872-66a1cf8bb2fb

      • Ondansetron- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 3 December 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ondansetron

      • Ondansetron 4mg Orodispersible Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 3 December 2021]. Available from:

        https://www.medicines.org.uk/emc/product/10164/smpc

      • Important Information About Ondansetron- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 3 December 2021]. Available from:

        https://www.drugsbanks.com/important-information-about-ondansetron/

      • ONDANSETRON- ondansetron hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2011 [Cited 3 December 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fc3d39e0-8bf2-4c29-b872-66a1cf8bb2fb

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
      swan-banner
      Sponsored

      Popular Questions & Answers

      View All

      What care needs to be taken by women to keep th...

      related_content_doctor

      Dr. Sonal Kumar

      Gynaecologist

      hello, a good healthy diet along with calcium and vit d supplements and a regular exercise regime..!

      Periodic onset of depression/fear/stress/inerti...

      related_content_doctor

      Dr. Karuna Chawla

      Homeopath

      Try to relax yourself -- Exercise. Exercise is one of the most important things you can do to com...

      I have pain on right side of forehead that is s...

      related_content_doctor

      Dr. Sharique Imbesat

      General Physician

      Hi Shahid It is either migraine or hemicrania Consult me with proper history so that I can figure...

      I am 21 years male there is sudden onset of inv...

      related_content_doctor

      Dr. Chandra Shekhar Sharma

      General Physician

      Welcome to lybrate, there can be something which is irritating motor nerve supply of your right c...

      She had a problem with menstrual cycle. What ar...

      related_content_doctor

      Dr. Vijay Kumar Aware Patil

      Ayurveda

      Yes. Practice vajarasan daily cap immugain cap detox cap omegarich cap cap green rich protirich w...

      Table of content

      Content Details
      Profile Image
      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
      Profile Image
      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
      chat_icon

      Ask a free question

      Get FREE multiple opinions from Doctors

      posted anonymously
      swan-banner