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Overview

Neostigmine

Prescription vs OTC : Prescription by Doctor required

About Neostigmine

Neostigmine is used in the treatment of Myasthenia gravis, Ogilvie syndrome and urinary retention. It is a cholinesterase inhibitor and a parasympathomimetic agent. It improves the transmission of nerve impulses.

On taking Neostigmine you may experience the following side effects; drowsiness, diarrhea, skin rash, indigestion, headache and vomiting. Major reactions include twitching, blurred vision, cough, chest pain, hives, difficulty in breathing and moving, muscle spasms, joint pains, seizures. In case effects persist or worsen, contact your health care provider immediately.

Before using Neostigmine, have a discussion with your doctor and avoid using it if you are pregnant, or planning to become pregnant or are breastfeeding, if you are taking any kind of prescription or non-prescription medications, if you have any allergies to medicines, foods, substances or any ingredients contained within Neostigmine, if you have heart diseases or any infections.

Neostigmine needs to be injected into a vein, muscle or below the skin. The dosage for you will be determined by your doctor based on your gender, age, medical history and current condition. Should you suspect a drug overdose, inform your doctor right away.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the uses of Neostigmine

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the side effects of Neostigmine ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Key highlights of Neostigmine

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Tilstigmin 15mg tablet may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Neostigmine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Medicines containing Neostigmine

    Below is the list of medicines, which contains Neostigmine as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    How does this medication work?

    This medication prevents the breakdown of acetylcholine by impeding acetylcholinesterase's actions. This helps in better muscular contraction, as more acetylcholine is available for binding with muscarinic and nicotinic receptors.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

      References

      • Neostigmine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 11 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/neostigmine

      • Neostigmine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 11 June 2022].Available from:

        https://go.drugbank.com/drugs/DB01400

      • NEOSTIGMINE injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 11 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=NEOSTIGMINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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