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Overview

Leuprorelin

Prescription vs OTC : Prescription by Doctor required

About Leuprorelin

Leuprorelin is used for the treatment of hormone-based tumour which includes prostate cancer, breast cancer, lymphoma, certain kinds of leukaemia, uterine fibroids, and endometriosis. This medicine is a synthetic version of a hormone called gonadotropin-releasing hormone (GnRH).

Apart from these, it is also used to treat the early onset of puberty. It is administered through an injection into a muscle or under the skin by a healthcare professional only. Prolonged usage leads to a substantial decline of testosterone in males and a decrease in estradiol in females.

It is also used to avoid premature ovulation in in-vitro fertilization processes. In some cases, this medication may be harmful if inhaled, can cause allergic skin reactions, asthma-like symptoms and breathing difficulties.

This drug is also used to delay puberty in transgender boys and girls until they are old enough to start hormone-replacement therapy. It has also been used on an experimental basis to reduce sexual urges in paedophiles and other kinds of paraphilias.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the uses of Leuprorelin

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the contraindications of Leuprorelin ?

    • Hypersensitivity

    • Vaginal Bleeding

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the side effects of Leuprorelin ?

    • Decreased Libido

    • Testicular Atrophy

    • Increased Sweating

    • Fatigue

    • Muscle Weakness

    • Erectile Dysfunction

    • Bone Pain

    • Hot Flashes

    • Injection Site Reaction

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Key highlights of Leuprorelin

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      This medication is highly unsafe to use during pregnancy.
      Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      This medication is not safe while driving.

    • Does this affect kidney function?

      There is no data available. Please consult a doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult a doctor before consuming the drug.

    • What is the onset of action?

      The effect of this medicine is shown after 60 - 90 minutes of administration.

    • How long is the duration of effect?

      The duration of action of medicine vary form person to person. This medicine shows a effect for about 7 to 10 days.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of this medication, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Medicines containing Leuprorelin

    Below is the list of medicines, which contains Leuprorelin as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    How does this medication work?

    This medicine belongs to the class of GnRH i.e. gonadotropin hormone receptor agonist. Its administration results in inhibiting the secretion of follicle stimulating and luteinizing hormones (FSH & LH), which leads to decrease the testosterone and estrogen level in blood.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

      What are the interactions of Leuprorelin ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medicine interacts with the following medicine Quinidine, Disopyramide, Amiodarone, Sotalol, Dofetilide, Ibutilide

      FAQs about Leuprorelin

      • Ques : What is Leuprorelin?

        Ans : This medication is a synthetic version of a hormone called gonadotropin-releasing hormone.

      • Ques : How long do I need to use Leuprorelin before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Leuprorelin?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Leuprorelin empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Leuprorelin?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Leuprorelin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 4 December 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/leuprorelin

      • Leuprolide- DrugBank [Internet]. Drugbank.ca. 2017 [Cited 4 December 2019]. Available from:

        https://www.drugbank.ca/drugs/DB00007

      • Prostap 3 DCS 11.25 mg Powder and Solvent for Prolonged-release Suspension for Injection in Pre-filled syringe- EMC [Internet] medicines.org.uk. 2019 [Cited 4 December 2019]. Available from:

        https://www.medicines.org.uk/emc/product/4651/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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