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Overview

Drotaverine

Prescription vs OTC : Prescription by Doctor required

About Drotaverine

Drotaverine effectively treats twitches or spasm of the smooth muscles generally found in the stomach and heart. It is effective in relieving pain triggered due to irritable bowel syndrome, headache, menstrual periods and cervical spasm during labour.

It is also effective in abdominal pain, chest pain, gallstones pain in the kidneys, pain in renal colic and a few other conditions. Drotaverine may interact with a few other drugs like Atropine, Diclofenac, Levodopa, and Diazepam. Inform your doctor about taking any other medications, before starting the course of this medicine.

The possible side-effects that may occur on using this medicine are nausea, vomiting, fainting, dry mouth, sleep disorders, constipation, flushing, allergic dermatitis, swelling of face, lips, eyelids, tongue, hands and feet, falling of blood pressure and change in pulse rate.

Drotaverine is not recommended in patients with severe heart, liver, and kidney disease. This drug should be used with caution in patients suffering from a genetic disorder of the skin and blood. It is also advised to avoid taking this medicine in People who are or have:

  • Allergic reactions,
  • are Pregnant or
  • Breastfeeding.

It comes as an oral medicine to take by mouth, with or without food. The recommended dose for adults is usually 40-80 mg, three times a day but it can vary depending on your condition. If taken orally as an antispasmodic by children between the age of 1 to 6, the recommended dose is 20 mg, three to four-time daily. In children older than 6 years of age, the dosage is generally increased to 40 mg.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Drotaverine

    • Smooth Muscle Spasm

    • Pain Relief

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Drotaverine ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Drotaverine ?

    • Nausea Or Vomiting

    • Dry Mouth

    • Change In Pulse Rate

    • Allergic Skin Reaction

    • Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet

    • Fall In Blood Pressure

    • Vertigo

    • Headache

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Drotaverine

    • How long is the duration of effect?

      The duration of time for which this medicine remains effective is not established clinically.

    • What is the onset of action?

      The amount of time taken for this medicine to show its effect is not established clinically.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use by pregnant women unless necessary and the benefits outweigh the risks.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use if you are breastfeeding as the risks of adverse effects on the infant are significantly high.

    • Is It safe with alcohol?

      It is unknown whether it is safe or not to take Drotaverine along with alcohol.

    • Is it safe to drive while on this medicine?

      Drotaverine may cause side effects which affects the alertness of the patient taking it. It can even cause vertigo.

    • Does this affect kidney function?

      Limited information is available on Drotaverine use in patients with kidney disease.

    • Does this affect liver function?

      Limited information is available on Drotaverine use in patients with liver disease.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

    • Are there any overdose instructions?

      In case of an overdose, doctor should be consulted immediately. The overdose symptoms are restlessness, confusion and dizziness. As per the severity of the symptoms, the supportive measures like gastric lavage are initiated.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Drotaverine approved?

    • India

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Medicines containing Drotaverine

    Below is the list of medicines, which contains Drotaverine as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This drug works by inhibiting the phosphodiesterase-IV enzymes and helping in restoring the balance of cyclic AMP and calcium ions at the site of spasm in smooth muscles.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Drotaverine ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Medicine

        Atropine

        Report the use of any medicine taken for pain to the doctor. You may require a dose adjustment and more frequent monitoring to use these medicines together.

        Diclofenac

        Report the use of any medicine taken for pain to the doctor. You may require a dose adjustment and more frequent monitoring to use these medicines together.

        Levodopa

        Use of this medicine in a patient taking levodopa should be avoided. The risk of adverse effects are significantly high and the symptoms might worsen after taking these medicines together. Use of an alternative medicine that is safer for use is recommended in such cases.

        Diazepam

        Report the use of any medicine taken for pain to the doctor. You may require a dose adjustment and more frequent monitoring to use these medicines together Report any incidence of adverse effects to the doctor on priority.
      • Interaction with Disease

        Porphyria

        This medicine should be used with caution in a patient suffering from this genetic disorder of the blood and skin.

        Low Cardiac Output

        This medicine is not recommended for use if you suffer from a condition that impairs the normal blood pumping ability of the heart.

      FAQs about Drotaverine

      • Ques : What is Drotaverine?

        Ans : This drug performs its action by obstructing the pain caused by irritable bowel syndrome.

      • Ques : What are the uses of Drotaverine?

        Ans : This drug is used for the treatment and prevention of conditions and symptoms of diseases like muscle twitches and cervical spasms.

      • Ques : What are the instructions for storage and disposal Drotaverine?

        Ans : This drug should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : Should I use Drotaverine empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication, work properly on an empty stomach.

      • Ques : Is there any food or drink I need to avoid?

        Ans : The diet should be normal, there is nothing as such to avoid.

      References

      • Drotaverine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 3 December 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/drotaverine

      • Drotaverine - DrugBank [Internet]. Drugbank.ca. 2021 [cited 3 December 2021]. Available from:

        https://go.drugbank.com/drugs/DB06751

      • Drotaverine - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2021 [cited 03 December 2021]. Available from:

        https://pubchem.ncbi.nlm.nih.gov/compound/1712095

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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