This is a combination medication which has Chloramphenicol and Hydrocortisone as active ingredients. It is a broad-spectrum antibiotic. This medicament is used for treating several severe bacterial infections. It is also used as an eye ointment to treat conjunctivitis. This medicament treats meningitis, cholera, plague and typhoid fever. It works by interfering with the growth of the bacteria causing the infection.
It is recommended to monitor blood cell levels, once in every two days during treatment. If you miss a scheduled dose of this medicine or if you suspect an overdose, seek medical attention as soon as possible. The duration for which this medicament remains effective usually varies according to the intended use and dosing regimen.
Following conditions can be restored by utilizing this prescription:
This medicament causes side effects such as:
Is It safe with alcohol?No interaction found
Are there any pregnancy warnings?This medicament is safe to use during pregnancy. Adequate and well-controlled human studies have shown low or no risk.
Are there any breast-feeding warnings?This medicament is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Is it safe to drive while on this medicine?This medicament may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
Does this affect kidney function?There is limited information available on the use of this medicament in patients with kidney disease. Please consult your doctor.
Does this affect liver function?There is no data available. Please consult doctor before consuming the drug.
Missed Dose instructionsContact your doctor immediately if you miss a scheduled dose of this medicine.
Overdose instructionsContact your doctor immediately if an overdose with this medicament is suspected.
This medicament is an antibiotic which works by reversibly binding to the 50S subunit of the ribosomes of the bacterial cell. It interferes with the activity of peptidyl transferase which in turn inhibits protein synthesis in the bacterial cells by blocking peptide bond formations. Hydrocortisone acts as a corticosteroid used for reducing skin inflammation. Your body releases different chemicals in response to certain triggers. Hydrocortisone works by stopping the infection-fighting white blood cells from reaching the part of your body which is prone to infections.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
AlcoholInteraction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
LabInformation not available.
Interaction with Medicine
WarfarinReport the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring of bleeding and clotting time while taking these medicines together.
Ethinyl EstradiolUse of this medicine can make hormonal oral contraceptives less effective and hence chances of unintended pregnancies increase. Alternate means of contraception should be adopted while taking this medicine.
CefiximeReport the use of either of the medicine to the doctor. You may need a dose adjustment and more frequent monitoring while taking them together. It is advised to inform the doctor about the use of any medicine belonging to cephalosporin group.
HydrocodoneReport the use of either of the medicine to the doctor. Your doctor will prescribe alternatives that have minimal or no interactions. An increase in side effects like drowsiness, dizziness, impairment of thinking should be reported to the doctor.
Iron and vitamin B12Use of chloramphenicol can interfere with the effect of iron and vitamin B12 for the treatment of anemia. Report the use of either of the medicine to the doctor. Do not stop the use of any medicine without consulting your doctor.
DeferiproneReport the use of any chemotherapy medicine to the doctor before receiving chloramphenicol. The risk of adverse effects are significantly high and hence your doctor may prescribe safer alternatives.
Interaction with Disease
Bone Marrow SuppressionUse of this medicament in patients having a suppressed bone marrow can lead to fatal adverse effects. It could lead to several diseases of the blood in such patients. This medicine should be administered with extreme caution in patients with bone marrow suppression.
Liver/Kidney ImpairmentThis medicine should be used with extreme caution in patients having an impairment of liver or/and kidney function. Use should be avoided unless absolutely necessary.
Interaction with Food
FoodInformation not available.
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.