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Doctors for Liddle Syndrome in Mangalore
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Lybrate User's review for Dr. Praveen Kumar Rai
He is very nice and soft spoken doctor and listen to patient nicely and brief them very well Read more reviews
Liddle syndrome is an inherited form of high blood pressure (hypertension). This condition is characterized by severe hypertension that begins unusually early in life, often in childhood, although some affected individuals are not diagnosed until adulthood. Some people with Liddle syndrome have no additional signs or symptoms, especially in childhood. However, overtime, untreated hypertension can lead to heart disease or stroke, which may be serious. Children are usually asymptomatic. Adults can present with symptoms of hypokalemia such as weakness, fatigue, myalgia, constipation or palpitations.
HOW IS LIDDLE SYNDROME DIAGNOSED?
It is confirmed by blood and urinary electrolyte tests which show hypokalemia, decreased or normal plasma levels of renin and aldosterone, metabolic alkalosis with high sodium plasma levels, and low rates of urinary excretion of sodium and aldosterone with high rates of urinary potassium excretion. The diagnosis is confirmed by genetic testing.
HOW IS LIDDLE SYNDROME TREATED?
The treatment is with a low sodium (low salt) diet and a potassium-sparing diuretic that directly blocks the sodium channel. Potassium-sparing diuretics that are effective for this purpose include amiloride and triamterene. Amiloride is the only treatment option that is safe in pregnancy. Medical treatment usually corrects both the hypertension and the hypokalemia and as a result these patients may not require any potassium replacement therapy.
DID YOU KNOW?
When left untreated, the condition can lead to heart based ailments and can be fatal.