Sclerosing Cholangitis is a disease of the bile ducts that causes scars in the bile ducts. These scars lead to hardening and narrowing of the bile ducts leading to gradual but serious liver damage. Early symptoms of the disease are fatigue and itching. The more prominent symptoms include pain in the upper abdomen, fever, chills, night sweats, enlarged liver, weight loss and jaundice.
HOW IS SCLEROSING CHOLANGITIS DIAGNOSED?
Diagnosis is first done based on clinical tests, physical examination and radiography results. Contrast cholangiography is considered one of the best diagnostic tests to detect the abnormality in the bile duct. This is followed by liver biopsy and transient elastography.
HOW IS SCLEROSING CHOLANGITIS TREATED?
The gastroenterologist may prescribe Ursodeoxycholic acid, glucocorticoids, methotrexate, penicillamine, anti TNF drugs along with antibiotics, cyclosporine, tacrolimus and various other medications. Surgical methods such as liver transplantation are also recommended.
DID YOU KNOW?
Sclerosing Cholangitis can be fatal leading to liver failure.