Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}

Prothrombin Time Health Feed

I am 12 years old. I have a problem called hemofilia, factor 13 deficiency. What is the temporary or permanent solution in ayurvedic treatment for this problem.

MD - Homeopathy, BHMS
Homeopath, Vadodara
I am 12 years old. I have a problem called hemofilia, factor 13 deficiency. What is the temporary or permanent soluti...
Hemofilia has no cure, so no temporary or permanent solution. You can do about it to be careful. Avoid any injury or bleeding.
Submit FeedbackFeedback

Hello sir I am hemophilia A and in my inhibitor report I got it positive what can a do for decreasing it?

MD - Obstetrtics & Gynaecology, FCPS, DGO, Diploma of the Faculty of Family Planning (DFFP)
Gynaecologist, Mumbai
Hello sir I am hemophilia A
and in my inhibitor report I got it positive
what can a do for decreasing it?
Most of medical challenges need doctor to listen to detailed medical history in form of questions and answers, examination of patient and sometimes reports so meet concerned doctor Haematologist.
Submit FeedbackFeedback

Hemophilia - What Exactly Is It?

MBBS, MD, FICH
Hematologist, Ludhiana
Hemophilia - What Exactly Is It?
Hemophilia is an inherited genetic disorder that impairs the body's ability to make blood clots because it lacks sufficient blood-clotting proteins (clotting factors).

Epidemiology
Hemophilia is rare, and it has only about one instance in every 10,000 births for hemophilia A and 1 in 50,000 births for hemophilia B. Hemophilia usually occur in males.

Types
There are two main types of hemophilia:

Hemophilia A: It occurs due to unavailability of enough clotting factor VIII.
Hemophilia B: It occurs due to unavailability of enough clotting factor IX.
Other types include:

Hemophilia C: It occurs due to unavailability of enough clotting factor XI.
Parahemophilia: It occurs due to unavailability of enough clotting factor V.
Acquired hemophilia: It is associated with cancers, autoimmune disorders, and pregnancy.
Causes
When a person bleeds, the body pools blood cells together to form a clot to stop the bleeding. The clotting process is encouraged by certain clotting factors.

Acquired hemophilia is a rare variant of the condition. It occurs when a person's immune system attacks clotting factors in the blood. It can be associated with the following factors:

Pregnancy
Autoimmune conditions
Cancer
Multiple sclerosis
Signs and Symptoms
It may vary, depending on the level of clotting factors. If the clotting factor level is mildly reduced, the patient may bleed only after surgery or trauma. If the deficiency is severe, the patient may experience spontaneous bleeding symptoms which include following signs and symptoms:

Unexplained and excessive bleeding from cuts or injuries, or after surgery, or dental work
Unusual bleeding after vaccinations
Blood in urine or stool
Nosebleed
Many large or deep bruises
Pain, swelling, or tightness in joints
In infants, there is presence of unexplained irritability
Bleeding into the brain leading to painful and prolonged headache, repeated vomiting, sleepiness or lethargy, double vision, sudden weakness or clumsiness, convulsions, or seizures

Complications
Deep internal bleeding
Damage to joints due to internal bleeding causing arthritis or destruction of the joint
Infection due to blood transfusions
In few people with hemophilia, the immune system has a negative reaction to the clotting factors used to treat bleeding. The immune system develops proteins (known as inhibitors) that inactivate the clotting factors, which make the treatment less effective

Diagnosis
Can be made with positive family history
A blood test can show a clotting-factor deficiency in children and adults
Some people come to know they have hemophilia after they bleed excessively during a surgical procedure

Treatment
Replacement of the specific clotting factor that body needs
Desmopressin (DDAVP): This hormone can stimulate your body to release more clotting factor
Clot-preserving medications (antifibrinolytic)
Fibrin sealants: Applied directly to wound sites to promote clotting and healing
2752 people found this helpful

All About Knee Replacement

DNB (Orthopedics), Diploma in Orthopaedics, MBBS
Orthopedic Doctor, Mumbai
All About Knee Replacement
Knee replacement is a surgery wherein an artificial joint is used to replace a diseased, damaged or worn out knee. This surgery is common among people who fall in the age group of 60-80, but recent trends seem to suggest that younger people are opting for this surgery as well. The lifetime of the artificial knee joint is around 20 years, provided the knee is well cared for.

Why do you need Knee Replacement?

Most common reason is high grade osteoarthritis due to wear and tear of the knee joint. The pre-hospital study of the Knee joint is mandatory and would decide what kind of Replacement is suitable to the patient. If there is diabetes or hypertension associated with this, then it should be controlled well before undergoing surgery. Hemoglobin of at least 10 gm% is required.

If the mobility in your knee joint is reduced leading to impaired functioning of the knee joint, then you might need a knee replacement surgery. You may experience pain while walking, sitting and, in some cases, resting as well.

Some of the common reasons why you may opt for this particular surgery are:

Gout, where, small crystals are formed inside the joint.
Rheumatoid Arthritis, an autoimmune disorder, wherein the immune system of the body attacks the body s healthy tissues.
Hemophilia, wherein, the blood ceases to clot normally.
Injuries to the knee
Disorders that cause unusual bone growth (bone dysplasias)
Death of bone in the knee joint following blood supply problems (avascular necrosis)
Knee deformity with pain and loss of cartilage
Unusual growth of bones in the knee joint
Knee replacement surgery is classified into:

1. Partial Knee Replacement: In this surgery, only one part of the joint is replaced.

2. Total Knee Replacement: Total knee replacement surgery involves replacement of both sides of the knee joint.

The usual hospital stay period is around 2-3 days after the surgery is completed. Initially, you will require the help of crutches to walk for at least 2 months. You may also be asked to do gentle knee strengthening exercises. It may take up to two years to recover completely from a knee replacement surgery.
4076 people found this helpful

Sir I am suffering from hemophelia I am 38 years old I am having problem in my knee joint due to which I am not able to walk freely and have to wait for seconds before starting walk after long sitting what should I do sir.

k
Orthopedic Doctor, Bilaspur
Did you injure your knee? I would recommend xray of both knees standing ap and lat views. Get your serum esr, ra, crp and aso.
2 people found this helpful
Submit FeedbackFeedback