Charcot-Marie-Tooth (CMT) Disease is the most common inherited neurological disease that affects the peripheral nerves. Charcot-Marie-Tooth Disease is also known as hereditary motor and sensory neuropathy. The neuropathy of CMT affects both motor and sensory nerves. Symptoms are:
• Weakness of foot and lower leg muscles
• Foot drop and high-stepped gait
• Foot deformities
• Weakness and muscle atrophy
HOW IS CHARCOT-MARIE-TOOTH DISEASE DIAGNOSED?
The diagnosis will be done by a specialist from the Neurology department who will begin with a physical examination that will check for reduced reflexes as well as deformities, especially in the foot. This will be followed by nerve conduction studies and a nerve biopsy, as well as genetic testing and Electromyography (EMG).
HOW IS CHARCOT-MARIE-TOOTH DISEASE TREATED?
There is no treatment for Charcot-Marie-Tooth disease, but symptomatic relief is possible. Physical and occupational therapy can help improve muscle strength. Wearing braces and other orthopaedic devices can help individuals cope with the disabilities caused by the disease. In some cases orthopaedic surgery may be required to reverse foot deformities
DID YOU KNOW?
A promising area of research on CMT is gene therapy experiments