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Dr. Prabir Kr Das

Pediatrician, Kolkata

460 at clinic
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Dr. Prabir Kr Das Pediatrician, Kolkata
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I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family....more
I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family.
More about Dr. Prabir Kr Das
Dr. Prabir Kr Das is an experienced Pediatrician in Mukundapur, Kolkata. You can visit him at Vision Care Hospital-Mukundapur in Mukundapur, Kolkata. Save your time and book an appointment online with Dr. Prabir Kr Das on Lybrate.com.

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Vision Care Hospital-Mukundapur

E.M. Bypass, mukundapur. Landmark:Behind Metro Cash & Carry Near Medica Hospital, KolkataKolkata Get Directions
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Diagnosing Thalassemia - How Can It Be Done?

MBBS Bachelor of Medicine and Bachelor of Surgery, MD - Medicine, DM - Clinical Hematology
Hematologist, Patna
Diagnosing Thalassemia - How Can It Be Done?

Thalassemia is a genetic (i.e., passed from parents to children through genes) blood disorder. People with Thalassemia disease are not able to make enough hemoglobin, which causes severe anemia. Hemoglobin is found in red blood cells and carries oxygen to all parts of the body. When there is not enough hemoglobin in the red blood cells, oxygen cannot get to all parts of the body. Organs then become starved for oxygen and are unable to function properly.

There are two types of Thalassemia disease- 

  1. Alpha Thalassemia disease: There are two main types of Alpha Thalassemia disease. Alpha Thalassemia Major is a very serious disease in which severe anemia begins even before birth. Pregnant women carrying affected fetuses are themselves at risk for serious pregnancy and delivery complications. Another type of Alpha Thalassemia is Hemoglobin H disease. There are varying degrees of Hemoglobin H disease.
  2. Beta Thalassemia disease: Beta Thalassemia Major (also called Cooley's Anemia) is a serious illness. Symptoms appear in the first two years of life and include paleness of the skin, poor appetite, irritability, and failure to grow. Proper treatment includes routine blood transfusions and other therapies.

Causes of Thalassemia-

Thalassemia occurs when there’s an abnormality or mutation in one of the genes involved in hemoglobin production. You inherit this genetic defect from your parents.

If only one of the parents is a carrier for thalassemia, the child may develop a form of the disease known as thalassemia minor. If this occurs, the born child probably won’t have symptoms, but he/she will be a carrier of the disease. Some people with thalassemia minor do develop minor symptoms.

If both of your parents are carriers of thalassemia, you have a greater chance of inheriting a more serious form of the disease.

Symptoms-

The symptoms depend on the type of thalassemia:

  • Thalassemia Minor: Thalassemia minor usually doesn’t cause any symptoms. If it does, it causes minor anemia.
  • Beta-thalassemia: Beta-thalassemia comes in two serious types, which are thalassemia major, or Cooley’s anemia, and thalassemia intermedia. The symptoms of thalassemia major generally appear before a child’s second birthday. The severe anemia related to this condition can be life-threatening. Other signs and symptoms include:
    • fussiness
    • paleness
    • frequent infections
    • a poor appetite
    • failure to thrive
    • jaundice, which is a yellowing of the skin or the whites of the eyes
    • enlarged organs

This form of thalassemia is usually so severe that it requires regular blood transfusions.

  • Alpha-thalassemia: Alpha-thalassemia also has two serious types, which are hemoglobin H disease and hydrops fetalis. Hemoglobin H disease can cause bone issues. The cheeks, forehead, and jaw may all overgrow. Hemoglobin H disease can cause:
    • jaundice, which is a yellowing of the skin or the whites of the eyes
    • an extremely enlarged spleen
    • malnourishment

Hydrops fetalis is an extremely severe form of thalassemia. It occurs before birth. Most individuals with this condition are either stillborn or die shortly after being born.

How is thalassemia diagnosed?

Thalassaemia is often detected during pregnancy or soon after birth.

  1. Screening during pregnancy: Screening to check if a baby is at risk of being born with thalassemia is offered to all pregnant women.
  2. Testing after birth or later in life: Newborn babies aren't routinely tested for thalassemia because the test used isn't always reliable soon after birth and the condition isn't immediately dangerous. However, the main form of the condition – beta thalassemia major – is often picked up as part of the newborn blood spot test (heel prick). A blood test can be carried out at any point to diagnose the condition if a child or adult has symptoms of thalassemia and the condition wasn't picked up earlier on.
  3. Testing for the Thalassemia Trait- A blood test can be done at any time to find out if you have the thalassemia trait and are at risk of having a child with the condition. This can be particularly useful if you have a family history of the condition or your partner is known to carry thalassemia.

If your child has thalassemia, blood tests may reveal:

  1. A low level of red blood cells
  2. Smaller than expected red blood cells
  3. Pale red blood cells
  4. Red blood cells that are varied in size and shape
  5. Red blood cells with uneven hemoglobin distribution, which gives the cells a bull's-eye appearance under the microscope

Blood tests may also be used to:

  1. Measure the amount of iron in your child's blood
  2. Evaluate his or her hemoglobin
  3. Perform DNA analysis to diagnose thalassemia or to determine if a person is carrying mutated hemoglobin genes

Treatment for Thalassemia-

The treatment for thalassemia depends on the type and severity of disease involved. Your doctor will give you a course of treatment that will work best for your particular case.

Some of the utilized treatments include:

  • blood transfusions
  • a bone marrow transplant (BMT)
  • medications and supplements
  • possible surgery to remove the spleen or gallbladder

In case you have a concern or query you can always consult an expert & get answers to your questions!

2583 people found this helpful

My son is 5.3yrs old, he has stuffed nose and cold.How do I identify the wheeze? Medication for cold?

FCCP (USA), MD - Pulmonary Medicine
Pulmonologist, Indore
Wheeze is a musical hissing sound which comes while breathing especially while exhaling the air. Usually they are found when patient is breathless during early morning hours.
13 people found this helpful
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My 5 months old baby has one undescended testicle. What is hcg treatment. Is surgery the only remedy?

Diploma In Child Health (DCH), MBBS
Pediatrician, Gurgaon
My 5 months old baby has one undescended testicle. What is hcg treatment. Is surgery the only remedy?
Hcg is harmonal injections. Sometimes hcg treatment works in making decent. Early the intervention better the results
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Common Allergies in Children That You Should Know!

MBBS Bachelor of Medicine and Bachelor of Surgery, BCH, DNB - Training, PDCC - Pediatric Hepatology & Gastroenterology
Pediatrician, Gurgaon
Common Allergies in Children That You Should Know!

A rash on your child’s body or their regular cough bouts can sometimes be triggered by an allergy. We can excuse it by calling it a common flu or a heat rash, but the reason behind it might be something you are not aware of. Your child might be allergic, and it is imperative for you to find out that exact thing your child is allergic to, it can be dust, nuts that you may think is beneficial for your child’s health or even the fabric of the clothes you put on them. Allergies are caused when children come in contact with allergens, which can he inhaled, injected or even eaten unknowingly. If you see any of the symptoms of allergies, consult your doctor at the earliest and do not treat it lightly.

Some common triggers for allergies

These are divided into four groups

  1. Foods: Certain foods like peanuts, eggs, milk and it products which you feed your child might be triggering their allergy.
  2. Outdoors: When kids play outside pollens from trees or flowers might causes allergies. Even insect bites and stings are a major trigger
  3. Indoors: Animal fur or hair and even dust mites and mold that exist in your house can trigger an allergy
  4. Irritants: Common irritants like cigarette smoke, perfumes or even car exhaust should be watched out for.

Symptoms of common allergies

  1. Nasal Congestion: It is referred to as stuffy nose, which is very common in kids. Allergies are the most common cause of chronic nasal congestion (a stuffy nose) in children. Sometimes a child’s nose is congested to the point that he or she breathes through the mouth, especially while sleeping.
  2. Allergic rhinitis (hay fever): It is also common and its symptoms include a runny or itchy nose and constant sneezing. A child with allergies may also have itchy, watery, red eyes and chronic ear problems. Even though it’s commonly known as “hay fever,” allergic rhinitis isn’t triggered by hay and doesn’t cause fever.

If you suspect your child has an allergy, make an appointment to see a specialist. Start a diary before the appointment and keep track of what symptoms your child experiences and what you think causes them.

3 people found this helpful

My younger daughter is 10 years old. She is not gaining her weight please suggest some diet for her.

MBBS, MD Pediatrics
Pediatrician, Delhi
Hi, following advices will help: dietary advice: child should be given food in addition to milk, like fruits: banana, apple, mango, chiku, rice, cereals, paneer, yoghurt, paranthas, eggs, ghee and butter in every meal. Investigations: complete blood count with peripheral smear treatment: depending on the report, multivitamin or iron syrup, appetizer syrup and deworming syrup also needs to be given. I hope this has helped you. Wishing your child good health.
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Mera beta 7 month ka hai use infection hogaya hai Dr. Ne use darolac acua dithi par iski jaga kya Mai entrogemina dedi to koi prblm to nai hai.

MD - Alternate Medicine, BHMS
Homeopath, Surat
Mera beta 7 month ka hai use infection hogaya hai Dr. Ne use darolac acua dithi par iski jaga kya Mai entrogemina ded...
please give Darolac Aqua only. And do not change the prescription on your own without doctor's recommendation, it could let us to side effects. Take care :)
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What is the ideal dose of syrup TANCET-COLD {i e each 5 ml contains*cetrizine 1 mg, phenylephrine 2.5 mg,paracetamol mg) for male baby 18 month old. Weight 10 kg.

Diploma in Child Health (DCH), F.I.A.M.S. (Pediatrics)
Pediatrician, Muzaffarnagar
What is the ideal dose of syrup TANCET-COLD {i e each 5 ml contains*cetrizine 1 mg, phenylephrine 2.5 mg,paracetamol ...
I never preferred FDC medicines that too cough syrup. Though you missed quantity of paracetamol even then there is no rational combination.
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Hi doctor I have one month old baby boy and am gaining weight constantly tummy is becoming fat. There is no menstrual discharge also. Kindly suggest me some solution.

MBBS, DGO, DNB (Obstetrics and Gynecology)
Gynaecologist, Chennai
Hi doctor
I have one month old baby boy and am gaining weight constantly tummy is becoming fat. There is no menstrual...
Hi, you have delivered just one month ago. Your menstruation may at art after a while if you are breast feeding. Also after six weeks if normal delivery and after 3 months if delivery is by c section you can start post natal exercises which will help you to get back in to your shape. Consult your obstetrician who did your delivery or a physiotherapist and learn the exercises.
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I am 40 years old. I had little enquiry my son 14 years old he had constipation problem from which sometimes he faces hyper acidity, stomach ache, n sometime vomiting due to hyperacidity. Pimples on his face do let know any medicine regarding this. Thanks.

Diploma in Child Health (DCH), F.I.A.M.S. (Pediatrics)
Pediatrician, Muzaffarnagar
For constipation, give him fibrous diet and adequate water. Encourage him to go toilet daily or may be twice in a day for developing bowel habit. Isabgol husk may be tried with plenty of water at bed time. Pimples are common at this age. Don't scratch it, apply calamine lotion and consult skin specialist.
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