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Dr. Anup Kumar Mitra

Cardiologist, Kolkata

Dr. Anup Kumar Mitra Cardiologist, Kolkata
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I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning....more
I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning.
More about Dr. Anup Kumar Mitra
Dr. Anup Kumar Mitra is a trusted Cardiologist in S P Mukherjee Road, Kolkata. You can visit him at Sadan Medical Center in S P Mukherjee Road, Kolkata. Book an appointment online with Dr. Anup Kumar Mitra and consult privately on Lybrate.com.

Lybrate.com has top trusted Cardiologists from across India. You will find Cardiologists with more than 44 years of experience on Lybrate.com. You can find Cardiologists online in Kolkata and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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135 L, S P Mukherjee Road, Kalighat, KolkataKolkata Get Directions
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I am 24, male.i have poor blood flow all over my body, having heart problem like bp and left chest stiffness and digestion problem. I have been having garlic daily for last 4 month, now , high BP totally gone, but some little discomfort on left chest still remains, please, guide how to get better health such as healthy heart, liver (mainly).{i do not smoke and drink}

Diploma in Child Health (DCH), MBBS
General Physician, Bangalore
I am 24, male.i have poor blood flow all over my body, having heart problem like bp and left chest stiffness and dige...
Sir, You need to furnish your full health record showing all your problems, treatment taken. now, including Lab investigations, so that proper advice can be given
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I have a problem with my heart. When I ran away for doing something I am getting tired. What should I do?

MBBS, cc USG
General Physician, Gurgaon
I have a problem with my heart. When I ran away for doing something I am getting tired. What should I do?
Problem of tiredness may be due to Any medical disease like Anaemia/ Hypoproteinemia/ Thyroid problem/Vit D deficiency Multi mineral and vitamin Deficiency Stress/ anxiety Over exertion (physical and mental) kindly follow advises given below: 1. Take adequate rest 2. Proper diet 3. I recommend you to take Tablet Daily(Nutrilite) after personal consultation this supplement has shown wonderful result Consult me for further management
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My husband has diabetes since about 20years and takes glucophage.He also has blood pressure of the similar duration of time and takes 25 mg of blood pressure medicine.Please do help

General Physician (AM)
Alternative Medicine Specialist, Chandigarh
,(biochemic) nat phos 30x 4 pills 4 times a day, avoid all types of fats and red meat. For diabetes ; (homeo) gymnema sylvestere q 7- drops n little water thrice a day.
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Dengue Vaxia

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician,
Dengue Vaxia

Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

More information about dengvaxia - first vaccine against dengue

Sanofi awaits govt approval to launch dengue vaccine in india

Sanofi pasteur - dengue vaccine frequently asked questions

13 people found this helpful

I have a fractured leg since one week and my weight is rising at a very high rate and cholesterol level too please suggest some diet measures to control weight.

PG Diploma in Emergency Medicine Services (PGDEMS), Bachelor of Ayurveda, Medicine and Surgery (BAMS), MD - Alternate Medicine
Ayurveda, Ghaziabad
I have a fractured leg since one week and my weight is rising at a very high rate and cholesterol level too please su...
Best way to reduce fat is exercise and diet control....take pranacharya medohar rasayn twice a day....medohar guggul 2-2 twice a day....and pranacharya slim capsule 1-1 twice a day...avoid junk food...oily food...fermented food..alcohol consumption..sugar....milk products and sweets....take oats and cereals more..and do pranayama early in the morning and walk for atleast 45 minutes a day...and do exercises....dont sleep immediately after taking meal...
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My Name is A. Girish Kumar. My mom is suffering with chest pain since long time. According to that I consulted the doctors in hospitals like Narayan Hrudayalaya, Jayadeva. As doctors said that, the problem is not related to heart, It's related to nervous, then I visited to Nimhans.

MBBS, cc USG
General Physician, Gurgaon
My Name is A. Girish Kumar. My mom is suffering with chest pain since long time. According to that I consulted the do...
If you are having chest pain due to Anxiety than this problem can be solved by meditation I can give you address of Rajyoga meditation center near your house (this is free of cost) Consult me privately
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My blood pressure is 170- 90 and my weight is 110. sir what is the risk and how can I reduce the weight and how can I reduce the bp?

M.Sc - Dietitics / Nutrition
Dietitian/Nutritionist, Bangalore
hello to reduce weight start regular exercise,never skip meals,include salads in every meal possible,keep sipping water,avoid sugar and processed foods, to reduce blood pressure cut down on slat, avoid papad,pickles or any processed foods
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I am 19 years old boy! Since last few days I am experiencing extreme sweat whenever I sit in my class. When at college lecture is going on I sweat tremendously from my face to waist. What may be the problem? What should I do? I just checked my bp weeks ago that was normal.

MBBS
General Physician, Jalgaon
I am 19 years old boy! Since last few days I am experiencing extreme sweat whenever I sit in my class.
When at colleg...
Please check your blood sugar levels check your thyroid hormone levels blood pressure send me report on lybrate meanwhile please reduce your wt by regular exercises and diet control avoid oily spicy and fast food avoid outside food totally avoid rice wake up early go for morning walk in greenery for 40 min minutes minimum do regular pranayam and yoga daily or join gym cap ayurslim by himalaya 2 2 after food for 6mths.
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I live in delhi . I am working professional .I am a 32 y old male and have a chest pain for last 3 months. What should I do/

M.B.B.S., Diploma in Family Medicine, Fellowship in Diabetes (Liverpool), Advanced Clinical Course in Cardiology (USA), Certified Diabetologist from USA, CCEBDM, MD - Consultant Physician
General Physician, Hooghly
Dear , chest pain may be due to various reasons like heart and lungs problems, digestion problems. You first do an ecg and get your blood pressure, pulse checked. Mention if your pain increases while hard work, climbing stairs, swallowing food. Describe if the pain is throbbing in nature or just a tightness feeling. Mention if the pain radiates to any part of your body. Wish u all the best. Dr. S. Modak
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I have high blood pressure, and my sugar is also high. What can be the treatment to control it.

CME Course in Diabetes for Family Physicians, Certificate in Child Health , BHMS
Homeopath, Gurgaon
I have high blood pressure, and my sugar is also high. What can be the treatment to control it.
If your BP and blood sugar are on the border-line or marginally high,you can take homoeopathic medicines.
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MY SISTER IS HAVING PAIN IN THE LOWER PART OF CHEST RIB BONE. IS THERE ANY PROBLEM? She had no injuries over there and she is experiencing pain alot. Help me plz. Help me plz.

MBBS
General Physician, Mumbai
MY SISTER IS HAVING PAIN IN THE LOWER PART OF CHEST RIB BONE. IS THERE ANY PROBLEM? She had no injuries over there an...
Dear lybrateuser, - She should avoid exertion, bending, lifting weight till pain subsides - do hot fomentation three times a day - apply pain killer gel lightly over affected area three times a day - if still pain is more then take pain killer tablet after meals 2-3 times a day - if not much relief then get x-ray chest done, consult a doctor.
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Meri elder Sister ko 3 December ko heart attack h .28 years age h unki & mere father ki death bhi heart attack se hui thi so me kese bach skta hu heart attack se?

PG Diploma in Emergency Medicine Services (PGDEMS), Bachelor of Ayurveda, Medicine and Surgery (BAMS), MD - Alternate Medicine
Ayurveda, Ghaziabad
Meri elder Sister ko 3 December ko heart attack h .28 years age h unki & mere father ki death bhi heart attack se hui...
Avoid eating oily food. Junk food. Walk for atleast 45 minutes a day. Do pranayama early morning. Avoid alcohol consumption and smoking.
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My father is having Concentrated Left ventricular hypertrophy. How can it be cured? Please help.

MBBS
General Physician, Mumbai
My father is having Concentrated Left ventricular hypertrophy. How can it be cured? Please help.
We need to examine your fathers vital parameters of the body and than if necessary we can start with frusemide
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Sir/mam My grandfather is left with only 40 percent of lungs and now he is suffering from blood pressure at the ratio of 36 (low bp)-60 (high bp). So, please tell me the future consequences he will face along with remedies we have to do for him. Waiting for your prompt reply soon. Thank you.

Diploma in Cardiology, MBBS
Cardiologist, Delhi
Sir/mam
My grandfather is left with only 40 percent of lungs and now he is suffering from blood pressure at the ratio...
Get 2d echo done to know the cardiac status. Yu have to find it out what is the cause of low bp. As you mentioned it's 60/30. He requires hospitalisation.
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I am a BP (140/100, or 140/90) patient. All the test results say nothing but I have BP. And recently I noticed some Gasping issue. Is it because of BT or some thing else and I am using Prolomet XL 25 is it safe is there any side effects.

MBBS, DMRD, MD - Radio Diagnosis, FIIM(Ayurved), D.SC, Post Doctoral Fellowship of Institute of Indian Medicine, Ph.D
Non-Invasive Conservative Cardiac Care Specialist, Ahmednagar
I am a BP (140/100, or 140/90) patient. All the test results say nothing but I have BP. And recently I noticed some G...
Dear It seems you ate stressed may be over worked Adequate rest, brisk walk, meditations, exercise over time will help Attend stress management courses. Add beet root in diet as salad.
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How to reduce cholesterol in blood? What type of foods can eat a cholesterol patient?

MBBS, MD-General Medicine, DM - Cardiology
Cardiologist, Secunderabad
How to reduce cholesterol in blood?
What type of foods can eat a cholesterol patient?
Three simple ways to reduce cholesterol. 1. Eat healthy: Diet rich in fruits n vegetables, low in fats and simple carbohydrates like sugar, more in fibre. What it means is avoid fast food, cola, snacks and fried items. Most home cooked foods prepared with less oil are healthy. Be mindful of calories. 2. Burn calories: Activities like walking, jogging, swimming, cycling are helpful. 3. Beyond these if cholesterol is still high and you have additional risk factors, your doctor may prescribe you cholesterol reducing medication.
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He is suffering from Heart attack and after 4 days brain attack What should be the future step to recover from this as early as possible.

MBBS
General Physician, Trivandrum
He is suffering from Heart attack and after 4 days brain attack
What should be the future step to recover from this a...
A balanced diet regular exercise avoid smoking and drinking stress free life avoiding processed foods, sugars regular checkups yoga, meditation and paranayam.
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What will fix a headach and fever for someone on blood pressure medicine? Please advise.

LCPS, BAM&S
General Physician, Pune
This certainly needs a look by your family doctor. This mostly is flu. Try first plain crocin tablets for 1-2 days. If there is no relief then see a doctor.
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