Sorry, your search did not match any doctors. Here are some other doctors that we have hand picked for you!
Show doctors near me
Pyoderma gangrenosum (PG) is a rare and serious skin disease in which a painful nodule or pustule breaks down to form a progressively enlarging ulcer. The name relates to the appearance of the ulcers, which have a purulent surface ('pyoderma') and a blue-black edge ('gangrenosum'). However, there is neither infection nor gangrene involved.
HOW IS PYODERMA GANGRENOSUM DIAGNOSED?
Pyoderma gangrenosum is diagnosed by its characteristic appearance. There is no specific test. The wound should be swabbed and cultured for micro-organisms, but these are not the cause of pyoderma gangrenosum. Biopsy may be necessary to rule out other causes of ulceration. Pyoderma gangrenosum characteristically results in a neutrophilic inflammatory infiltrate but this is not always present. The pathergy test is usually positive (a skin prick test causing a papule, pustule or ulcer).
HOW IS PYODERMA GANGRENOSUM TREATED?
No single, specific treatment exists and few controlled trials of treatment have been done.16 Most clinicians use a stepwise approach and both topical and systemic treatments. Immunosuppression is the mainstay of treatment, and the most commonly used drugs are corticosteroids and ciclosporin. Several other immunosuppressive agents have been used with varied results, but treatment is largely empirical and the choice of treatment often depends on local experience.
DID YOU KNOW?
It is characterized by small, red bumps or blisters (papules or nodules) that eventually erode to form swollen open sores (ulcerations). The size and depth of the ulcerations vary greatly, and they are often extremely painful.