Sorry, your search did not match any doctors. Here are some other doctors that we have hand
picked for you!
Show Doctors near me
That's all we have from Perumpilly, Kochi. Here are some top doctors from nearby cities
Papillon–Lefèvre syndrome is also referred to as PLS and palmoplantar keratoderma and it is an autosomal recessive genetic disorder. The cause of this problem is deficiency in cathepsin C. The patient here would experience extreme signs of weakness in gums and destructions of periodontium. This usually commences after the 4th molar tooth comes out and teeth are lost before the age of 4.
HOW IS PAPILLON-LEFÈVRE SYNDROME DIAGNOSED?
Diagnosis is done by a dentist who would observe the loss of teeth pattern and also do a blood test and tissue test.
HOW IS PAPILLON-LEFÈVRE SYNDROME TREATED?
The treatment of Papillon-Lefèvre Syndrome is directed toward the specific symptoms that are apparent in each individual. Treatment may require the coordinated efforts of a team of specialists. Physicians may carefully monitor affected individuals to help prevent and ensure early identification of infection. Should gum infection occur antibiotic therapy may be prescribed. In some cases, surgery and skin grafts may be used to alleviate skin problems. Use of antiperspirants and deodorants may help with excessive perspiration. Genetic counseling may be of benefit for affected individuals and their families. Other treatment is symptomatic and supportive. Treatment with vitamin A (retinoids) has been found helpful in treating some individuals with Papillon-Lefèvre Syndrome.
DID YOU KNOW?
Skin abnormalities may sometimes be apparent at birth or during infancy.