The Hailey-Hailey Disease is a genetic disorder that causes blisters on the skin. The most common areas for the infection are the neck, armpits and skin folds of the arms and legs. The most prominent symptom is the sudden outbreak of rashes, blisters along the skin folds that are painful.
HOW IS HAILEY-HAILEY DISEASE DIAGNOSED?
A diagnosis of Hailey-Hailey disease is made based upon a thorough clinical evaluation, a detailed patient history, identification of characteristic findings and a variety of specialized tests including the surgical removal and microscopic examination (biopsy) of affected skin tissue. A biopsy may reveal abnormal formation of keratin tissue and failure of cell-to-cell adhesion. Blood tests in individuals with Hailey-Hailey disease will fail to detect antibodies.
HOW IS HAILEY-HAILEY DISEASE TREATED?
There is no cure for Hailey-Hailey disease. Treatment is aimed at reducing symptoms and preventing flares.
• Avoiding trigger factors such as sunburn, sweating and friction helps to control the disease.
• Wear absorbent pads in underwear
• Corticosteroid creams
• Combination corticosteroid/ antibiotic creams.
• Prolonged courses of oral antibiotics.
• Phototherapy (ultraviolet light) has also been used.
• Photodynamic therapy has had varying success.
• Lasers have been reported to be useful in one study, vaporising the affected skin.
• In severe cases surgery can be performed to remove the affected skin. Skin grafts are usually necessary to repair the wounds.
DID YOU KNOW?
Long-term corticosteroid therapy is not recommended because it can further weaken damaged skin