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CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY
It is the most common form of hereditary stroke disorder, and is thought to be caused by mutations of the Notch 3 gene on chromosome 19. It may start with attacks of migraine with aura or subcortical transient ischemic attacks or strokes, or mood disorders between 35 and 55 years of age. The disease progresses to subcortical dementia associated with pseudobulbar palsy and urinary incontinence.
HOW IS CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY DIAGNOSED?
Diagnosing the symptoms of this condition is not always easy as an effective diagnosis will require a biopsy of a sample of brain tissue. Normal physical examination along with a CT scan and imaging tests can be conducted by a neurologyspecialist if the condition is suspected.
HOW IS CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY TREATED?
Currently, there are no treatments available for curing the disease or preventing its onset. Treatment may be given for symptomatic relief and to improve the quality of life of the patient
DID YOU KNOW?
In individuals with CADASIL, a stroke can occur at any time from childhood to late adulthood, but typically happens during mid-adulthood. People with CADASIL often have more than one stroke in their lifetime. Recurrent strokes can damage the brain over time.