Alexander disease also known as fibrinoid leukodystrophy is a fatal neurological disease. It is very rare and genetic in nature. It mostly affects infants and children causing delayed developments in physical growth. The symptoms of this disease are: • Infantile Alexander Disease • Megalencephaly • Hydrocephalus: • Failure to thrive • Seizures: • Spasticity/spastic quadriparesis: • Progressive Psychomotor Retardation
HOW IS ALEXANDER DISEASE DIAGNOSED?
Diagnosis can be done through common tests conducted in neurology such as genetic testing of blood samples. Otherwise symptoms like large head size, or MRI scans can also be helpful.
HOW IS ALEXANDER DISEASE TREATED?
There is currently no cure or standard procedure for treating Alexander disease. However, patients are advised to seek pediatric and neurological expertise.
DID YOU KNOW?
Alexander disease is not a genetically inherited disease, where neither of the parents have genetic defect. This genetic disease is sometimes called sporadic, meaning that the defect occurred spontaneously.