Doctors for Fanconi Anemia in C.R.R Puram, Kanchipuram
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Fanconi Anemia is an extremely rare genetic disease that affects the bone marrow. Patients suffering from Fanconi Anemia have a reduced production of all types of blood cells. It is caused by an abnormal gene that damages cells, which prevents them from repairing damaged DNA. Symptoms are:
• Abnormal heart, lungs and digestive tract
• Bone problems
• Changes in skin colour
• Deafness due to abnormal ears
• Abnormal kidney function
• Short height
• Small heads, genitals and testicles
HOW IS FANCONI ANEMIA DIAGNOSED?
Common tests for Fanconi anemia include:
Bone marrow biopsy
Complete blood count (CBC)
Drugs added to a blood sample to check for damage to chromosomes
Hand x-ray and other imaging studies (CT scan, MRI)
HLA tissue typing (to find matching bone-marrow donors)
Ultrasound of the kidneys
Pregnant women may have amniocentesis or chorionic villous sampling to diagnose the condition in their unborn child.
HOW IS FANCONI ANEMIA TREATED?
Patients with mild to moderate blood cell changes who do not need a transfusion may only need regular check-ups and blood count checks. Medicines called growth factors (such as erythropoietin, G-CSF, and GM-CSF) can improve blood counts for a short while. A bone marrow transplant can cure the blood count problems of Fanconi's anemia. (The best donor is a brother or sister whose tissue type matches the patient.)
Hormone therapy combined with low doses of steroids (such as hydrocortisone or prednisone) is prescribed to those who do not have a bone marrow donor. Most patients respond to hormone therapy. But everyone with the disorder will quickly get worse when the drugs are stopped. In most cases, these drugs eventually stop working. Additional treatments may include:
1. Antibiotics (possibly given through a vein) to treat infections
2. Blood transfusions to treat symptoms due to low blood counts
Also ayurvedic and homeopathic medications are used to treat this condition
DID YOU KNOW?
The condition is usually diagnosed in children between 2 and 15 years old. Persons with this disorder are more likely to develop several types of blood disorders and cancers, including leukemia, myelodysplastic syndrome, and cancer of the head, neck, or urinary system.