Chronic granulomatous disease is an inherited disorder in which certain immune system cells do not function properly. This leads to ongoing and severe infection. About half of CGD cases are passed down through families and sex-linked trait. Boys are more likely to get the disorder than girls. CGD can cause many types of skin infections that are not easy to treat, including:
• Blisters or sores on the face (impetigo)
• Growths filled with pus (abscesses)
• Pus-filled lumps in the skin (boils)
HOW IS CHRONIC GRANULOMATOUS DISEASE DIAGNOSED?
Tests, that may be done by a dermatologist, include:
• Bone scan
• Chest x-ray
• Complete blood count (CBC)
• Flow cytometry tests to help confirm the disease
• Nitroblue tetrazolium test (NBT) to help diagnose the disease and find out whether the mother is a carrier
• Genetic testing to confirm the diagnosis
• Tissue biopsy
HOW IS CHRONIC GRANULOMATOUS DISEASE TREATED?
The treatment will be carried out by the general physician with the help of antibiotics and predisone on a long term basis. Steroids and antifungal therapy may also prove useful.
DID YOU KNOW?
People with CGD should avoid swimming except in chlorinated water to avoid infections as their immunity is very low.