It is a disorder characterized by abnormal bone tissue in the lower part of the face. Beginning in early childhood, both the lower jaw and the upper jaw become enlarged as bone is replaced with painless cyst-like growths. The symptoms are:
1. Swollen cheeks
2. Prominent lower face
3. Enlarged jaw
4. Abnormal teeth
5. Thick gums
6. Enlarged lymph nodes under jaw
HOW IS CHERUBISM DIAGNOSED?
Diagnosis of Cherubism is done based on dental abnormalities. Dentists may look for premature deciduous teeth and abnormal growth of permanent teeth. Genetic diagnosis is the final tool for confirming diagnosis. Sequence analysis of t he SH3BP2 gene confirms diagnosis
HOW IS CHERUBISM TREATED?
In most cases of cherubism, the disease improves and the abnormalities disappear with time. Severe cases may require surgery to eliminate excessive growth of cysts and tissues
DID YOU KNOW?
Cherubism was first documented and named by Dr. W.A. Jones in the year 1933, describing a case of three siblings belonging to the same family.