MELAS is the abbreviation of Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes and is related to a variety of mitochondrial cytopathies that also include MERRF, and Leber's hereditary optic neuropathy. This is an inherited condition and symptoms of disorder commence early in childhood ranging from loss of muscles, extreme weakness, dizziness and laziness and also seizures.
HOW IS MELAS SYNDROME DIAGNOSED?
Paediatricians conduct a complete physical evaluation and evaluate symptoms. Clinical tests may include measurement of lactate and pyruvate concentrations. Brain imaging may be conducted to detect stroke like signs. Electrocardiogram may be conducted to detect abnormalities in heart rhythm. Molecular genetic testing is the best way to confirm diagnosis.
HOW IS MELAS SYNDROME TREATED?
There is no treatment for this disease which is fatal. Enzymes, amino acids, antioxidants and vitamins could be prescribed depending on which part of the body is affected.
DID YOU KNOW?
This inherited disorder usually begins between the ages of 2 -15 years. The mutated gene that causes this syndrome is inherited only from the mother.